Diabetic kidney disease: Are the reported associations with single-nucleotide polymorphisms disease-specific?

Table 4 The distribution of genetic risk score in particular end-stage kidney disease subgroups

Group	GRS	P value	Post-hoc analysis
Classification: (1) GD, (2) TID, (3) VD, (4) CCD, (5) CP
		0.09	GD vs TID	P = 0.014
			GD vs VD	P = 0.12
GD (n = 146)	0.628 ± 0.256		GD vs CCD	P = 0.61
TID (n = 16)	0.461 ± 0.218		GD vs CP	P = 0.97
VD (n = 33)	0.551 ± 0.269		TID vs VD	P = 0.24
CCD (n = 13)	0.590 ± 0.138		TID vs CCD	P = 0.18
CP (n = 19)	0.629 ± 0.298		TID vs CP	P = 0.051
			VD vs CCD	P = 0.64
			VD vs CP	P = 0.29
			CCD vs CP	P = 0.66
Classification: (1) GD, (2) TID+VD+CCD, (3) CP
GD (n = 146)	0.628 ± 0.256	0.055	GD vs TID+VD+CCD	P = 0.018
TID+VD+CCD (n = 62)	0.536 ± 0.235		GD vs CP	P = 0.97
CP (n = 19)	0.629 ± 0.298		TID+VD+CCD vs CP	P = 0.16
Classification: (1) GD, (2) TID+VD+CCD+CP
GD	0.628 ± 0.256	0.051	N/A
TID+VD+CCD+CP	0.558 ± 0.253

Genetic risk score is presented as mean ± SD. GRS: Genetic risk score; GD: Glomerular disease; TID: Tubulointerstitial disease; VD: Vascular diseases; CCD: Cystic and congenital disease; CP: Complex pathogenesis; N/A: Not applicable.