Effect of liraglutide on endoplasmic reticulum stress in the renal tissue of type 2 diabetic rats

doi:10.4239/wjd.v11.i12.611

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Dec 15, 2020 (publication date) through May 1, 2024

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Dec 15, 2020; 11(12): 611-621
Published online Dec 15, 2020. doi: 10.4239/wjd.v11.i12.611

Table 2 Changes in biochemical indices in rats from each group

Biochemical index	Control group	Model group	Low-dose liraglutide group	High-dose liraglutide group
Scr (µmol/L)	51.05 ± 2.14	74.14 ± 4.36¹	64.40 ± 0.68²	58.39 ± 2.80³
BUN (mmol/L)	4.82 ± 0.61	9.72 ± 0.89¹	8.21 ± 0.92²	6.26 ± 0.46³
24-h urine protein (g/24 h)	0.35 ± 0.18	3.51 ± 0.81¹	2.34 ± 0.39²	1.48 ± 0.41³

¹Indicates significant differences in comparison with the control group.

²Indicates significant differences in comparison with the model group.

³Indicates significant differences in comparison with the low-dose liraglutide group. Scr: Serum creatinine; BUN: Blood urea nitrogen.

Citation: Zhao XY, Yu TT, Liu S, Liu YJ, Liu JJ, Qin J. Effect of liraglutide on endoplasmic reticulum stress in the renal tissue of type 2 diabetic rats. World J Diabetes 2020; 11(12): 611-621
URL: https://www.wjgnet.com/1948-9358/full/v11/i12/611.htm
DOI: https://dx.doi.org/10.4239/wjd.v11.i12.611