Association between restrictive pulmonary disease and type 2 diabetes in Koreans: A cross-sectional study

doi:10.4239/wjd.v11.i10.425

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Oct 15, 2020 (publication date) through May 24, 2024

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Diabetes. Oct 15, 2020; 11(10): 425-434
Published online Oct 15, 2020. doi: 10.4239/wjd.v11.i10.425

Table 1 Characteristics of individuals with normal, restrictive, and obstructive pulmonary disease

	Normal, n = 2177	RPD, n = 251	OPD, n = 402
Age (yr)¹	53.50 ± 0.27^a	57.79 ± 0.81^b	62.40 ± 0.65^c
Male (%)¹	45.1^a	50.8^a	78.5^b
T2DM (%)¹	7.9^a	21.1^b	12.2^c
HOMA-IR¹	2.10 ± 0.07^a	3.13 ± 0.41^b	2.21 ± 0.14^a
HOMA-beta¹	78.51 ± 2.50^a	83.13 ± 4.07^b	76.23 ± 3.83^c
HbA1c (%)¹	5.71 ± 0.02^a	6.14 ± 0.09^b	5.93 ± 0.06^bc
Hs-CRP (mg/L)¹	1.07 ± 0.05^a	1.79 ± 0.19^b	1.48 ± 0.17^a
Fasting insulin (UIU/mL)¹	7.80 ± 0.16^a	9.84 ± 0.61^b	8.07 ± 0.43^a
BMI (kg/m²)¹	24.08 ± 0.07^a	25.67 ± 0.23^b	24.08 ± 0.16^a
Fasting glucose (mg/dL)¹	101.99 ± 0.67^a	116.33 ± 3.64^b	105.85 ± 1.62^c
Waist circumference (cm)¹	82.97 ± 0.22^a	87.59 ± 0.60^b	86.29 ± 0.45^b
SBP (mmHg)¹	119.46 ± 0.42^a	123.83 ± 1.27^b	124.47 ± 0.85^b
DBP (mmHg)¹	77.22 ± 0.26	76.53 ± 0.86	76.27 ± 0.659
Total cholesterol (mg/dL)¹	197.35 ± 0.89^a	190.21 ± 2.59^b	191.86 ± 2.43^b
LDL-cholesterol (mg/dL)¹	118.97 ± 0.81^a	114.61 ± 2.21^a	116.41 ± 2.37^b
HDL-cholesterol (mg/dL)¹	50.73 ± 0.34^a	47.97 ± 0.88^b	46.62 ± 0.68^b
Triglyceride (mg/dL)¹	148.73 ± 3.28^a	155.62 ± 11.25^b	157.15 ± 7.17^c
Smoking status (%) (non-/ex-/current smoker)¹	57.6/24.2/18.3^a	56.7/25.3/18.0^a	30.8/40.3/28.9^b
Drinking alcohol status (%) (non-/current drinking)	25.6/74.4	30.5/69.5	23.3/76.7
FVC (% predicted)¹	3.69 ± 0.02^a	2.88 ± 0.04^b	3.83 ± 0.07^a
FEV1 (L)¹	2.93 ± 0.02^a	2.29 ± 0.04^b	2.48 ± 0.05^c
FEV1/FVC¹	0.80 ± 0.00^a	0.80 ± 0.00^a	0.64 ± 0.00^b
PEF (L/s)¹	7.75 ± 0.06^a	6.55 ± 0.12^b	6.67 ± 0.11^b

¹P < 0.05 by ANOVA or chi-square test. ^a,b,cThe same letters indicate non-significant difference between groups based on Bonferroni multiple comparison test. Data were presented as means ± SD or n (%). T2DM: Type 2 diabetes mellitus; Hs-CRP: Hs-C-reactive protein; BMI: Body mass index; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; LDL-cholesterol: Low density lipoprotein-cholesterol; HDL-cholesterol: High density lipoprotein-cholesterol. FVC: Forced vital capacity; FEV1: Forced expiratory volume 1.

Citation: Lee DY, Nam SM. Association between restrictive pulmonary disease and type 2 diabetes in Koreans: A cross-sectional study. World J Diabetes 2020; 11(10): 425-434
URL: https://www.wjgnet.com/1948-9358/full/v11/i10/425.htm
DOI: https://dx.doi.org/10.4239/wjd.v11.i10.425