Bone health in diabetes and prediabetes

doi:10.4239/wjd.v10.i8.421

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 10, Issue 8

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (9608)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-1) series, Tables (1-2) series.

Item

Count

PDF

857

WORD

268

HTML

5860

Figures (1-1)

375

Tables (1-2)

194

Sum=7554

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

873

Download

1181

Sum=2054

Aug 15, 2019 (publication date) through Apr 22, 2024

Times Cited of This Article

Times Cited (54)

Journal Information of This Article

Publication Name

World Journal of Diabetes

ISSN

1948-9358

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Review

World J Diabetes. Aug 15, 2019; 10(8): 421-445
Published online Aug 15, 2019. doi: 10.4239/wjd.v10.i8.421

Table 1 Bone turnover markers in prediabetes/insulin resistance and type 2 diabetes

BTM	Meaning	Pre-DM / IR	Ref.	T2D	Ref.
CTX	Bone resorption	↓ or ↔	[136,276,278-280]	↓	[129,132,134,137,281-286]
TRAP	Bone resorption	↑?	[287]	↓ or ↔	[132,281]
uNTX	Bone resorption			↓	[285]
Sclerostin	Inhibition of bone formation	↑	[65]	↑	[284,285,288,289]
OC	Bone formation	↓ or ↔	[128,276-278,280,290]	↓ or ↔	[129,132,134,281,283,285,286,291-294]
P1NP	Bone formation	↓ or ↔	[136,277,280]	↓ or ↔	[88,132,134,137,282,283,285,286]
BAP	Bone formation	Direct association with IR	[295]	↔ or ↓ or ↑	[132,281,284,286,292,294]
ALP	Bone formation	?	^?	↔ or ↑	[292-294]
OPG	Inhibition of bone resorption	↑	[296]	↑	[293,296]

BTM: Bone turnover marker; pre-DM: Prediabetes; IR: Insulin resistance; T2D: Type 2 diabetes; CTX: Carboxy-terminal cross-linking telopeptide of type I collagen; OC: Osteocalcin; P1NP: Procollagen type 1 amino-terminal propeptide; TRAP: Tartrate-resistant acid phosphatase; uNTX: Urinary N-telopeptide of type I collagen; BAP: Bone-specific alkaline phosphatase; ALP: Alkaline phosphatase; OPG: Osteoprotegerin; ↑: Increased; ↓: Decreased; ↔: Similar to healthy controls; ?: Unknown.

Citation: Costantini S, Conte C. Bone health in diabetes and prediabetes. World J Diabetes 2019; 10(8): 421-445
URL: https://www.wjgnet.com/1948-9358/full/v10/i8/421.htm
DOI: https://dx.doi.org/10.4239/wjd.v10.i8.421