Neurodegeneration: An early event of diabetic retinopathy

doi:10.4239/wjd.v1.i2.57

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May 15, 2010 (publication date) through Apr 23, 2024

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. May 15, 2010; 1(2): 57-64
Published online May 15, 2010. doi: 10.4239/wjd.v1.i2.57

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Figure 2 AT1-R activation by angiotensin II produced by the retina stimulates several pathways involved in the pathogenesis of DR such as inflammation, oxidative stress, leukostasis and angiogenesis. AT1-R:Angiotensin II type 1 receptor; AT2-R: Angiotensin II type 2 receptor; AGEs: Advanced glycated end products; BM: Basal membrane; BRB: Blood retinal barrier; ECM: Extracellular matrix; VEGF: Vascular endothelial growth factor.

Citation: Villarroel M, Ciudin A, Hernández C, Simó R. Neurodegeneration: An early event of diabetic retinopathy. World J Diabetes 2010; 1(2): 57-64
URL: https://www.wjgnet.com/1948-9358/full/v1/i2/57.htm
DOI: https://dx.doi.org/10.4239/wjd.v1.i2.57