Clinical usefulness of linked color imaging in identifying Helicobacter pylori infection: A systematic review and meta-analysis

Table 1 Characteristics of the enrolled studies

Ref.	Country	Trial design	Participants (M/F)	Mean age (yr)	Definitive test for H. pylori	Cases of H. pylori infection
Lee et al[19], 2020	United Kingdom	Single center, prospective	100 (58/42)	51.2	RUT	37
Ono et al[20], 2020	Japan	Multiple centers, prospective	127 (66/61)	62.4	UBT, serum antibody test	64
Wang et al[23], 2019	China	Single center, retrospective	103 (42/61)	48.0	RUT, histological staining	27
Dohi et al[22], 2016	Japan	Single center, retrospective	60 (37/23)	67.4	RUT, UBT, serum antibody test	30
Nakashima et al[17], 2020	Japan	Single center, prospective	120 (-)	57.2	UBT, serum antibody test	40
Nakashima et al[18], 2018	Japan	Single center, prospective	120 (-)	-	Serum H. pylori, IgG test	60
Sun et al[21], 2019	China	RCT	Group A: 127 (66/61)	47.2	RUT, histological staining	64
			Group B: 126 (68/58)	49.7		57

H. pylori: Helicobacter pylori; RUT: Rapid urease test; UBT: Urea breath test; IgG: Immunoglobulin G; RCT: Randomised controlled trial; M/F: Male/female.