Vonoprazan 20 mg vs lansoprazole 30 mg for endoscopic submucosal dissection-induced gastric ulcers

Table 2 The evaluation of the endoscopic submucosal dissection induced ulcers and delayed bleeding

	Vonoprazan	Lansoprazole	P value1	U value2
Area of the ulcer just after ESD (mm3)	1446.9 (605-3977.4)	1262.6 (597.8-7322.3)		89
Results of the follow-up endoscopy
Area of the ulcer on day 8 (mm3)	533.5 (93.6-1735.9)	459.8 (90.5-5479.5)		93
Shrinking rate on day 8 (%)	61.8 (24.0-91.1)	71.3 (25.2-88.6)		70.5
Area of the ulcer on day 28 (mm3)	61.6 (0-289.1)	28.7 (1.1-639.4)		93
Shrinking rate on day 28 (%)	95.3 (76.2-100)	97.2 (81.1-99.8)		68
Delayed ulcer healing n (%)	3/14 (21.4)	1/12 (8.3)	0.356
Delayed bleeding n (%)	0/14 (0)	0/12 (0)	1

¹χ²;

²Mann-Whitney U test. Data were expressed as number (%), mean ± SD, or median (range). U value less than 45 and P value less than 0.05 were considered statistically significant. ESD: Endoscopic submucosal dissection.