Endoscopic retrograde cholangiography for pediatric choledocholithiasis: Assessing the need for endoscopic intervention

doi:10.4253/wjge.v8.i11.425

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Endosc. Jun 10, 2016; 8(11): 425-432
Published online Jun 10, 2016. doi: 10.4253/wjge.v8.i11.425

Table 3 Univariate characteristics in the evaluation of choledocholithiasis

Criteria	Sensitivity% (95%CI)	Specificity% (95%CI)	PPV% (95%CI)	NPV% (95%CI)	Odds ratio (95%CI)	P-value
VS-PM	81.2 (64-91)	85.7 (42-99)	96.8 (81-100)	46.2 (20-74)	25.7 (2.65-249)	0.07
S-PM	59.5 (42-75)	85.7 (42-99)	95.7 (76-100)	28.6 (12-52)	8.8 (0.96-80.7)	0.001
VS-Adult	59.5 (42-75)	100 (56-100)	100 (81-100)	31.8 (15-55)	¹8.8 (0.96-80.7)	0.0001
S-Adult	48.6 (32-65)	85.7 (42-99)	94.7 (72-100)	24 (10-45)	5.68 (0.62-51.97)	0.0001
CBDS by US	43.2 (28-60)	100 (56-100)	100 (76-100)	25 (11-45)	¹4.57 (0.50-41.9)	0.0001
CBD > 6 mm	81.1 (64-91)	14.3 (1-58)	83.3 (67-93)	12.5 (1-33)	0.714 (0.074-6.92)	1
CBD > 8 mm	91.7 (76-98)	28.6 (5-70)	86.8 (71-95)	40 (7-83)	4.4 (0.58-33.2)	0.727
TB > 4.0	21.6 (10-39)	100 (56-100)	100 (60-100)	19.4 (8-37)	11.66 (0.17-15.82)	0.0001
TB ≥ 1.8	56.8 (41-71)	85.7 (49-97)	95.5 (75-100)	27.3 (12-50)	7.88 (0.86-72.12)	0.0001
CB ≥ 0.5	67.6 (50-81)	85.7 (42-99)	96.2 (78-100)	33.3 (14-59)	12.5 (1-115)	0.003
ALT > 300	56.8 (40-72)	14.3 (1-58)	77.8 (57-91)	5.9 (0-31)	0.219 (0.024-2.00)	0.052
ALT > 350	40.5 (26-57)	100 (56-100)	100 (80-100)	24.1 (11-42)	¹4.1 (0.45-37.5)	0.0001
AST > 155	43.2 (28-60)	85.7 (42-99)	94 (69-100)	22.2 (9-43)	4.57 (0.499-41.9)	0.0001
γGT > 400	35.1 (21-53)	100 (56-100)	100 (72-100)	22.6 (10-42)	¹3.25 (0.352-30.0)	0.0001

¹A zero denominator was substituted with a unit of one for odds ratio only. Includes sensitivity, specificity, positive predictive value, and odds ratio. P-values were calculated for each category for differences between patients with and without stones using McNemar’s test. PPV: Positive predictive value; NPV: Negative predictive value; VS-PM: Very Strong Pediatric “Modified”; S-PM: Strong Pediatric “Modified”; VS-Adult: Very Strong Adult; S-Adult: Strong Adult; CBDS: Common bile duct stone; CB: Conjugated bilirubin; TB: Total bilirubin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; γGT: Gamma-glutamyl transferase; CBD: Common bile duct.

Citation: Fishman DS, Chumpitazi BP, Raijman I, Tsai CMW, Smith EO, Mazziotti MV, Gilger MA. Endoscopic retrograde cholangiography for pediatric choledocholithiasis: Assessing the need for endoscopic intervention. World J Gastrointest Endosc 2016; 8(11): 425-432
URL: https://www.wjgnet.com/1948-5190/full/v8/i11/425.htm
DOI: https://dx.doi.org/10.4253/wjge.v8.i11.425