Systematic Reviews
Copyright ©The Author(s) 2015.
World J Gastrointest Endosc. Dec 25, 2015; 7(19): 1341-1349
Published online Dec 25, 2015. doi: 10.4253/wjge.v7.i19.1341
Table 2 Summary and strength of the evidence from trials analysed on GradePro®
Author(s): Sajid et al
Date: 20/10/2015
Question: NSAID’s are an effective modality to reduce the incidence of post-ERCP pancreatitis?
Settings: All patients undergoing booth elective or emergency ERCP in endoscopy department for any indication by an experienced gastroenterologist/endoscopists
Bibliography: Adapted from the Cochrane Database of Systematic Reviews [2015, Issue (Is)]
Quality assessmentNo. of patientsEffectQuality
Importance
No. of studies
Design
Risk of bias
Inconsistency
Indirectness
Imprecision
Other considerations
NSAID's vs placebo
Control
Relative(95%CI)
Absolute
Incidence of overall pancreatitis (follow-up mean 3 mo; assessed with: Odds ratio)
14Randomised trialsSeriousNo serious inconsistencyNo serious indirectnessNo serious imprecisionStrong association138/1900248/1878OR 0.49 (0.36 to 0.67)63 fewer per 1000 (from 40 fewer to 80 fewer)HighCritical
(7.3%)(13.2%)
15.7%73 fewer per 1000 (from 46 fewer to 94 fewer)