Pancreatic cystic lesions: How endoscopic ultrasound morphology and endoscopic ultrasound fine needle aspiration help unlock the diagnostic puzzle

Table 1 Cystic lesions of the pancreas[19] (reprinted with permission of Dr. Parra-Herran CE)

Cystic lesions of the pancreas
Non-neoplastic cysts (30%-40%)
No lining
Inflammatory pseudocyst
Paraduodenal wall cyst
Infection-related cyst
True lining
Mucinous non-neoplastic cysts (mucoceles, retention cysts)
Cystic hamartoma
Enterogenous (congenital, duplication) cyst
Endometriotic cyst
Lymphoepithelial cyst
Squamoid cyst of pancreatic ducts
Others (unclassified)
Neoplastic cysts (60%-70%)
True lining
Mucinous lining (30%)
Intraductal papillary mucinous neoplasm (20%)
Mucinous cystic neoplasm (10%)
Serous lining (20%)
Serous cystadenoma (microcystic, oligocystic)
Von Hippel-Lindau-associated pancreatic cyst
Serous cystadenocarcinoma
Squamous lining (< 1%)
Epidermoid cyst within intrapancreatic accessory spleen
Dermoid cyst
Acinar cell lining (< 1%)
Acinar cell cystadenoma
Acinar cell cystadenocarcinoma
Endothelial lining (< 1%)
Lymphangioma
Solid tumors with cystic change (5%)
Solid pseudopapillary tumor
Ductal adenocarcinoma with cystic change
Neuroendocrine tumor with cystic change
Other invasive carcinomas with cystic change
No lining (< 1%)
Mesenchymal neoplasms with cystic change
Others (unclassified)