Staining for p53 and Ki-67 increases the sensitivity of EUS-FNA to detect pancreatic malignancy

Table 2 Distribution of positive tumor marker stains, alone or in select parallel combinations, according to cytology and final diagnosis

Malignant (n=49)				Final diagnosis cytology	Benign (n=12)
Benign (n=8)	Atypical (n=17)	Suspicious (n=4)	Malignant (n=20)		Benign (n=5)	Atypical (n=7)	Suspicious (n=0)	Malignant (n=0)
1	4	0	9	p53	0	0	0	0
2	4	0	14	Ki-67	0	0	0	0
6	8	1	15	CEA	4	3	0	0
4	10	0	13	CA19-9	1	2	0	0
2	6	0	16	p53:Ki-67	0	0	0	0
6	12	1	17	p53:Ki-67:CEA	4	3	0	0
5	14	0	19	p53:Ki-67:CA19-9	1	2	0	0
6	15	1	19	All 4 stains	4	3	0	0

CEA: carcinoembryonic antigen.