From surface to depth: Combining white-light and ultrasound endoscopy to predict complete response in rectal cancer

doi:10.4253/wjge.122124

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Endosc. Aug 16, 2026; 18(8): 122124
Published online Aug 16, 2026. doi: 10.4253/wjge.122124

Table 2 Correlation between endoscopic biopsy and assessment of histologic response

Biopsy histology, n	CR	Non-CR	Total	Diagnostic performance	Value (%)
Negative	2	1	3	Accuracy	77.8
Positive	1	5	6	Sensitivity	66.7
Adenoma	0	1		Specificity	83.3
LGD	1	0		PPV	66.7
HGD	0	2		NPV	83.3
Adenocarcinoma	0	2		Youden’s index	0.5
Total	3	6	9	(P = 0.226)

LGD: Low-grade dysplasia; CR: Complete response; HGD: High-grade dysplasia; PPV: Positive predictive value; NPV: Negative predictive value.

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Citation: Chi J, Weng J, Li WH, Bai KH, Yang R, Zhang LJ, Fan WH, Wu XJ. From surface to depth: Combining white-light and ultrasound endoscopy to predict complete response in rectal cancer. World J Gastrointest Endosc 2026; 18(8): 122124
URL: https://www.wjgnet.com/1948-5190/full/v18/i8/122124.htm
DOI: https://dx.doi.org/10.4253/wjge.122124

Chi J, Weng J, Li WH, Bai KH, Yang R, Zhang LJ, Fan WH, Wu XJ. From surface to depth: Combining white-light and ultrasound endoscopy to predict complete response in rectal cancer. World J Gastrointest Endosc 2026; 18(8): 122124 [DOI: 10.4253/wjge.122124]

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