Predictors of incomplete common bile duct stone clearance at index endoscopic retrograde cholangiopancreatography

doi:10.4253/wjge.v18.i5.118389

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Endosc. May 16, 2026; 18(5): 118389
Published online May 16, 2026. doi: 10.4253/wjge.v18.i5.118389

Table 1 Univariate analysis on predictors of common bile duct stone clearance, n (%)

Parameters	Not cleared (n = 66)	Cleared (n = 179)	P value
Demographic and clinical parameters
Age (years)	49.5 (40-58)	45 (33-58)	0.1307
Gender (male:female)	17:49	43:136	0.908
Pain abdomen	58 (87.8)	133 (74.3)	0.0264
Jaundice	21 (31.8)	40 (22.3)	0.1302
Baseline lab parameters
Hb (g/dL)	11.9 (10.5-12.97)	11.9 (10.9-12.7)	0.83
TLC (cells/mm³)	7600 (6550-8790)	7600 (6450-9100)	0.85
Platelets (cells × 10⁵/mm³)	2.3 (1.63-2.87)	2.3 (1.7-3.0)	0.59
Total bilirubin (mg/dL)	0.9 (0.5-2.05)	0.7 (0.5-1.3)	0.076
ALT (IU/L)	34 (20-94)	42 (23-83)	0.28
AST (IU/L)	38.5 (27-75.5)	41 (26-78)	0.97
ALP (IU/L)	188 (129-346)	180 (127-312)	0.86
MRCP variables
CBD diameter > 15 mm	13 (19.7)	19 (10.6)	0.06
CBD diameter in mm	11.93 ± 4.57	10.68 ± 3.41	0.02
Stone number (> 3)	3 (4.5)	12 (6.7)	0.52
Stone size > 12 mm	16 (24.2)	16 (8.9)	0.001
Stone size (mm)	9.97 ± 4.90	7.73 ± 3.36	0.0001
Location of stone (proximal)	12 (18.2)	18 (10.1)	0.57
Stone to CBD diameter > 1	26 (39.3)	28 (15.6)	0.0014
ERCP variables
PAD	6 (9.1)	17 (9.5)	0.94
Bulky papilla	6 (9.1)	5 (2.8)	0.03
Difficult cannulation	16 (24.2)	14 (7.8)	0.001
CBD diameter > 15 mm	9 (13.6)	20 (11.2)	0.10
CBD Diameter (mm)	13.11 ± 5.10	11.72 ± 3.34	0.02
Stone number (> 3)	3 (4.5)	19 (10.6)	0.51
Stone size (mm)	13.77 ± 6.03	8.93 ± 3.89	0.0001
Location of stone (proximal)	8 (12.1)	18 (10.05)	0.02
CBD stricture	4 (6.1)	3 (1.6)	0.05
Hepatolithiasis	8 (12.1)	10 (5.6)	0.08
Impacted stone	16 (24.2)	5 (2.8)	0.0001
Use of a basket for extraction	1 (1.5)	3 (1.7)	0.94
Balloon sphincteroplasty	15 (19.7)	61 (80.2)	0.067

ALP: Alkaline phosphatase; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; CBD: Common bile duct; ERCP: Endoscopic retrograde cholangiopancreatography; Hb: Hemoglobin; MRCP: Magnetic resonance cholangiopancreatography; PAD: Periampullary diverticulum; TLC: Total leukocyte count.

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Citation: Lone SA, Vaithiyam V, Vora K, Sirohi N, Sonika U, Dalal A, Kumar A, Srivastava S, Sachdeva S, Sharma BC. Predictors of incomplete common bile duct stone clearance at index endoscopic retrograde cholangiopancreatography. World J Gastrointest Endosc 2026; 18(5): 118389
URL: https://www.wjgnet.com/1948-5190/full/v18/i5/118389.htm
DOI: https://dx.doi.org/10.4253/wjge.v18.i5.118389

Lone SA, Vaithiyam V, Vora K, Sirohi N, Sonika U, Dalal A, Kumar A, Srivastava S, Sachdeva S, Sharma BC. Predictors of incomplete common bile duct stone clearance at index endoscopic retrograde cholangiopancreatography. World J Gastrointest Endosc 2026; 18(5): 118389 [DOI: 10.4253/wjge.v18.i5.118389]

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