Moderate sedation with midazolam and propofol is as safe as propofol monotherapy for colonoscopy, but more cost-effective

doi:10.4253/wjge.v18.i4.118261

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Endosc. Apr 16, 2026; 18(4): 118261
Published online Apr 16, 2026. doi: 10.4253/wjge.v18.i4.118261

Table 2 Relevant results, mean ± SD

	Propofol combination therapy	Propofol monotherapy	P value
Dose of propofol (mg)	65 ± 21	217 ± 61	< 0.01
Duration of examination (minute)	21.4 ± 6	18.6 ± 6	0.02
Duration until discharge (minute)	49.4 ± 17	57.7 ± 26	0.04

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Citation: Ott C, Dobsch P, Sander M, Schnoy E, Pawlik MT. Moderate sedation with midazolam and propofol is as safe as propofol monotherapy for colonoscopy, but more cost-effective. World J Gastrointest Endosc 2026; 18(4): 118261
URL: https://www.wjgnet.com/1948-5190/full/v18/i4/118261.htm
DOI: https://dx.doi.org/10.4253/wjge.v18.i4.118261

Ott C, Dobsch P, Sander M, Schnoy E, Pawlik MT. Moderate sedation with midazolam and propofol is as safe as propofol monotherapy for colonoscopy, but more cost-effective. World J Gastrointest Endosc 2026; 18(4): 118261 [DOI: 10.4253/wjge.v18.i4.118261]

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