Moderate sedation with midazolam and propofol is as safe as propofol monotherapy for colonoscopy, but more cost-effective

doi:10.4253/wjge.v18.i4.118261

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Endosc. Apr 16, 2026; 18(4): 118261
Published online Apr 16, 2026. doi: 10.4253/wjge.v18.i4.118261

Table 1 Patient characteristics, mean ± SD/median (interquartile range)

	Propofol combination therapy	Propofol monotherapy	P value
Intervention	2.5 mg midazolame + propofol	Propofol monotherapy
Number of patients	60 (female 30, male 30)	60 (female 29, male 31)
Age (years)	55.5 (50-69)	57 (50-69)	0.96
BMI (kg/m²)	25.4 ± 3.37	26 ± 3.03	0.33

BMI: Body mass index.

Full Size Table

Citation: Ott C, Dobsch P, Sander M, Schnoy E, Pawlik MT. Moderate sedation with midazolam and propofol is as safe as propofol monotherapy for colonoscopy, but more cost-effective. World J Gastrointest Endosc 2026; 18(4): 118261
URL: https://www.wjgnet.com/1948-5190/full/v18/i4/118261.htm
DOI: https://dx.doi.org/10.4253/wjge.v18.i4.118261

Ott C, Dobsch P, Sander M, Schnoy E, Pawlik MT. Moderate sedation with midazolam and propofol is as safe as propofol monotherapy for colonoscopy, but more cost-effective. World J Gastrointest Endosc 2026; 18(4): 118261 [DOI: 10.4253/wjge.v18.i4.118261]

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