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World J Gastrointest Endosc. Mar 16, 2026; 18(3): 114327
Published online Mar 16, 2026. doi: 10.4253/wjge.v18.i3.114327
Table 2 Computed tomography grading of acute caustic injury as per the Ryu and Chirica classification
Grade
CT findings
Clinical implication
Ryu classification
Grade 1No definite swelling of esophagus wall (< 3 mm, within normal limit)No injury
Grade 2Edematous wall thickening (> 3 mm) without periesophageal soft tissue infiltrationUsually mild injury; often managed conservatively; low risk of complications
Grade 3Edematous wall thickening with periesophageal soft tissue infiltration plus well-demarcated tissue interfaceModerate injury; risk of stricture formation; close monitoring required
Grade 4Edematous wall thickening with periesophagealSevere injury; high risk of progression; surgical evaluation considered
Soft tissue infiltration plus blurring of the tissue
Interface or localized fluid collection around esophagus or descending aorta
Chirica classification
Grade 1Normal appearing GI tractNo injury
Grade 2Wall edema, surrounding soft tissue inflammation and increased postcontrast wall enhancementMild to moderate risk of injury; moderate to high risk of stricture formation
Grade 3Transmural necrosis, as shown by the absence of postcontrast wall enhancement with surrounding soft tissue inflammationModerate injury; risk of stricture formation; close monitoring required


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