Reduction of serum bilirubin levels after endoscopic biliary drainage in patients with extrahepatic biliary obstruction and its significance

Table 4 Multivariate analysis to assess the impact of bilirubin dynamics on reintervention

Variables	Model 1 (> 50% in bilirubin by day 7)		Model 2 (bilirubin < 3 mg/dL by day 15)
	Odds ratio (95%CI)	P value	Odds ratio (95%CI)	P value
All patients
Benign etiology	0.235 (0.024-2.348)	0.218	0.200 (0.021-1.880)	0.159
No cholangitis at baseline	4.528 (0.966-21.235)	0.055	5.258 (1.091-25.348)	0.039
Baseline bilirubin < 10 mg/dL	1.467 (0.286-7.513)	0.646	2.512 (0.422-14.955)	0.312
Failure to achieve > 50% in bilirubin by day 7	4.751 (1.035-21.086)	0.045	-	-
Failure to achieve bilirubin < 3 mg/dL by day 15	-	-	4.411 (0.795-24.475)	0.090
Malignant etiology
No cholangitis at baseline	3.555 (0.689-18.333)	0.130	4.039 (0.780-20.901)	0.096
Baseline bilirubin < 10 mg/dL	1.085 (0.173-6.807)	0.930	1.813 (0.262-12.554)	0.547
Failure to achieve > 50% in bilirubin by day 7	5.473 (1.089-27.498)	0.039	-	-
Failure to achieve bilirubin < 3 mg/dL by day 15	-	-	4.406 (0.776-25.030)	0.094

CI: Confidence intervals.