Reduction of serum bilirubin levels after endoscopic biliary drainage in patients with extrahepatic biliary obstruction and its significance

Table 1 Baseline characteristics of the patients included in the present study, n (%)/median (interquartile range)

Parameters	Total (n = 101)	Benign (n = 40)	Malignant (n = 61)	P value
Age, years	56 (22-92)	50 (22-79)	58 (26-92)	0.008
Male gender	55 (54.5)	23 (57.5)	32 (52.5)	0.618
Comorbidities	27 (26.7)	12 (30)	15 (24.6)	0.548
Diabetes mellitus	15 (14.8)	8 (20)	7 (11.5)
Hypertension	2 (2.0)	1 (2.5)	1 (1.6)
DM + hypertension	5 (4.9)	1 (2.5)	4 (6.5)
Others	5 (4.9)	2 (5)	3 (4.9)
Cholangitis	52 (51.5)	23 (57.5)	29 (47.5)	0.327
Leucocyte count, × 103 per mm3	10.35 (4.69-44.0)	10.23 (5.6-34.1)	10.74 (4.69-44.0)	0.843
PT-INR	1.2 (0.9-4.1)	1.2 (1.0-3.2)	1.3 (0.9-4.1)	0.044
Serum creatinine, mg/dL	0.7 (0.4-5.7)	0.8 (0.4-5.7)	0.6 (0.4-2.9)	0.069
Total bilirubin level, mg/dL	11.8 (6.0-30.2)	9.9 (6.0-24.7)	13.5 (6.1-30.2)	0.008
Alkaline phosphatase, IU/L	368 (109-2000)	360 (119-1500)	372 (109-2000)	0.034
Plastic stent	94 (93.1)	40 (100)	54 (88.5)	0.040

DM: Diabetes mellitus; PT: Prothrombin time; INR: International normalized ratio.