Endoscopic management of intestinal strictures in Crohn’s disease: Current status and future perspectives

doi:10.4253/wjge.123858

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Endosc. Oct 16, 2026; 18(10): 123858
Published online Oct 16, 2026. doi: 10.4253/wjge.123858

Table 7 Selected key evidence studies of colonic stenting in Crohn’s disease strictures

Ref.	Design	Patients/stent type	Key outcomes	Complications/surgery
Loras et al[93], 2022 (ProtDilat)	Multicentre RCT	FCSEMS vs EBD (maximum 2 sessions) (n = 80)	51% intervention-free at 1 year (vs 80% EBD)	Low severe AEs (~3% perforation)
Chandan et al[91], 2023	Systematic review & meta-analysis	163 patients (SEMS-fully/partially covered or biodegradable)	Technical 93%; clinical 61%	Migration common (44%); 11% repeat stenting
Scotti et al[92], 2023	Systematic review	173 patients	Technical success 95%; clinical success 100% for successfully placed stents; long-term efficacy 56%	Major complications 11%; surgery ~20%
Giri et al[94], 2022	Meta-analysis	170 patients	Technical success 98.2%; clinical success 71.3%	Stent migration 32%; post-procedural pain 20%; surgery rates 8.6%

RCT: Randomized controlled trial; FCSEMS: Fully covered self-expanding metal stents; EBD: Endoscopic balloon dilation; AEs: Adverse events; SEMS: Self-expanding metal stents.

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Citation: Mundhra SK, Singh AK, Kochhar R, Manrai M. Endoscopic management of intestinal strictures in Crohn’s disease: Current status and future perspectives. World J Gastrointest Endosc 2026; 18(10): 123858
URL: https://www.wjgnet.com/1948-5190/full/v18/i10/123858.htm
DOI: https://dx.doi.org/10.4253/wjge.123858

Mundhra SK, Singh AK, Kochhar R, Manrai M. Endoscopic management of intestinal strictures in Crohn’s disease: Current status and future perspectives. World J Gastrointest Endosc 2026; 18(10): 123858 [DOI: 10.4253/wjge.123858]

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