Comparative outcomes of laparoscopic vs open pancreaticoduodenectomy in early-stage pancreatic cancer

doi:10.4253/wjge.v18.i1.114791

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Endosc. Jan 16, 2026; 18(1): 114791
Published online Jan 16, 2026. doi: 10.4253/wjge.v18.i1.114791

Table 3 Oncologic outcomes, mean ± SD

Indicator	LPD group (n = 50)	OPD group (n = 50)	t/χ²	P value	MD/OR/HR (95%CI)
Lymph nodes retrieved	14 ± 5	13 ± 4	0.75	0.45	MD 1 (-0.77 to 2.77)
R0 resection (no/yes)	4/46	6/44	0.34	0.56	OR 1.57 (0.41 to 5.93)
Median OS [months (95%CI)]	22 (19-25)	20 (17-23)		0.65	HR 0.92 (0.65 to 1.31)
12-month RFS (%)	78	72		0.48	HR 0.78 (0.35 to 1.74)
Adjuvant completion (no/yes)	8/42 (84%)	10/40 (80%)	0.24	0.62	OR 1.31 (0.47 to 3.66)

OS: Overall survival; CI: Confidence interval; RFS: Recurrence-free survival; LPD: Laparoscopic pancreaticoduodenectomy; OPD: Open pancreaticoduodenectomy; OR: Odds ratio.

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Citation: Kalim M, Sarwar M, Chishti SSA, Ali M, Qayyum S, Ahmed J, Memon M, Shenawa E. Comparative outcomes of laparoscopic vs open pancreaticoduodenectomy in early-stage pancreatic cancer. World J Gastrointest Endosc 2026; 18(1): 114791
URL: https://www.wjgnet.com/1948-5190/full/v18/i1/114791.htm
DOI: https://dx.doi.org/10.4253/wjge.v18.i1.114791

Kalim M, Sarwar M, Chishti SSA, Ali M, Qayyum S, Ahmed J, Memon M, Shenawa E. Comparative outcomes of laparoscopic vs open pancreaticoduodenectomy in early-stage pancreatic cancer. World J Gastrointest Endosc 2026; 18(1): 114791 [PMID: 41607390 DOI: 10.4253/wjge.v18.i1.114791]

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