Low-volume bowel preparation provides safe and effective pan-enteric capsule endoscopy in suspected or established Crohn’s disease

Table 5 Characteristics of three historical cohorts using the high-volume preparation protocol

Ref.	CD status	n	Sex	VCE completion rate	Location at the end of the incomplete study (n)	True retention	SB adequate preparation rate	Colonic adequate preparation rate
Leighton et al[24], 2017	Active CD	721	Male 306%; female 611%; unknown 8.3%	91.7%	SB (5); stomach (1)	0	87.9%	39.4%-62.9%
Bruining et al[27], 2020	Active CD	119	Male 40%; female 60%	85.6%	Requested removal (1); SB (1); colon (16)	13	79%-90%	64%
Eliakim et al[26], 2020	CD in remission	542	Male 500%; female 259%; unknown 24.1%	92.6%	SB (2); colon (1)	0	94.4	75%

¹In the original study, 6/72 patients were excluded due to incomplete pan-enteric capsule endoscopy.

²There were 54 pan-enteric capsule endoscopies performed in 41 patients.

³1 patient - capsule was retrieved by dilation of the small bowel stricture through ileo-colonoscopy.

PCE: Pan-enteric capsule endoscopy; CD: Crohn’s disease; SB: Small bowel; VCE: Video capsule endoscopy.