Endoscopic ultrasound in the management of complications related to cirrhosis- recent evidence

doi:10.4253/wjge.v17.i9.108549

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Endosc. Sep 16, 2025; 17(9): 108549
Published online Sep 16, 2025. doi: 10.4253/wjge.v17.i9.108549

Table 1 Characteristics of the included studies on endoscopic ultrasound-guided portal pressure measurement

Ref.	Type of study	Number of studies included in manuscript	Country	Number of patients	Mean age (years)	Male/female	Comments/major findings
Laleman et al[2]	Review	20	United States	N/A	N/A	N/A	EUS-guided portal pressure measurement viable alternative for HVPG
Kolb et al[4]	Retrospective	1	United States	385	57.23	188/197 (51.2)	First multicenter study evaluating EUS-guided portal pressure measurement
Huang et al[5]	Prospective	1	United States	28	63	18/10 (36)	EUS-portal pressure gradient measurement showing 100% success and no adverse events
Laleman et al[6]	Review	135	United States	N/A	N/A	N/A	Suggests EUS-guided portal pressure gradient measurement is adequate alternative to hepatic vein catheterization
Choi et al[7]	Retrospective	1	United States	64	57.5	40/25 (37.5)	EUS-guided portal pressure gradient measurements have excellent correlation with histological hepatic fibrosis stage
Hajifathalian et al[8]	Prospective	1	United States	24	53	5/19 (79)	EUS-guided portosystemic pressure gradient combined with EUS-guided liver biopsy feasible, safe, accurate
Choi et al[9]	Retrospective	1	United States	83	59.4	51/32 (39)	Larger retrospective study showing EUS-guided portal pressure gradient measurement showing gradient was higher in patients with cirrhotic features
Zhang et al[10]	Prospective	1	China	12	63	9/3 (25)	EUS-guided portal pressure gradient measurement using 22-gauge fine-needle aspiration safe and accurate
Gadour et al[11]	Systematic review and meta-analysis	45	10 countries worldwide	N/A	N/A	N/A	Meta-analysis showing success rate of over 95% of EUS-guided portal pressure gradient measurement
Vanderschueren et al[12]	Prospective	Recruiting	Pending	Recruiting	Pending	Pending	Active study to evaluating head-to-head comparison of HVPG and EUS-guided portal pressure measurement

EUS: Endoscopic ultrasound; HVPG: Hepatic venous pressure gradient; N/A: Not available.

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Citation: Castleberry DT, Mann R, Tharian B, Thandassery RB. Endoscopic ultrasound in the management of complications related to cirrhosis- recent evidence. World J Gastrointest Endosc 2025; 17(9): 108549
URL: https://www.wjgnet.com/1948-5190/full/v17/i9/108549.htm
DOI: https://dx.doi.org/10.4253/wjge.v17.i9.108549

Castleberry DT, Mann R, Tharian B, Thandassery RB. Endoscopic ultrasound in the management of complications related to cirrhosis- recent evidence. World J Gastrointest Endosc 2025; 17(9): 108549 [PMID: 40979066 DOI: 10.4253/wjge.v17.i9.108549]

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