Impact of gastric neoplasms location on clinical outcome of patients treated by endoscopic submucosal dissection

Table 5 Gastric endoscopic submucosal dissection learning curve analysis for proximal stomach, n (%)

	Phase I (16 cases)	Phase II (16 cases)	Phase III (17 cases)	P value
En bloc resection	15 (93.7)	14 (87.5)	13 (76.4)	0.296
Complete resection (R0)	14 (87.5)	11 (68.7)	11 (64.7)	0.540
Curative resection	12 (75.0)	10 (62.5)	10 (58.8)	0.540
Size (mean), mm	17.2 (10-35)	28.6 (15-40)	32.7 (12-80)	0.035
Procedure time, mean ± SD, minutes	110.3 ± 52.8	126.2 ± 63.6	145.0 ± 67.2	0.348
Adverse events
Overall adverse event rate	0	0	5.8 (1/17)	0.540
Digestive bleeding	0	0	5.8 (1/17)	0.540
Perforation	0	0	0	1
Histological type of lesions
Benign neoplasms	6 (37.5)	5 (31.2)	0	0.296
Low grade dysplasia	2 (12.5)	2 (12.5)	4 (23.5)	0.540
High grade dysplasia	1 (6.2)	2 (12.5)	9 (52.9)	0.296
Adenocarcinoma (according to depth of tumor invasion)
Intramucosal	3 (18.7)	5 (31.2)	2 (11.7)	1
SM1 invasion	1 (6.2)	0	1 (5.8)	1
SM2 invasion	3 (18.7)	2 (12.5)	1 (5.8)	0.296

SM: Submucosal.