Endoscopic resection of colorectal laterally spreading tumors: Clinicopathologic characteristics and risk factors for treatment outcomes

Table 6 Univariate and multivariate analysis of risk factors for complications after endoscopic treatment of colorectal laterally spreading tumors

Variables	Univariate		Multivariate
	OR (95%CI)	P value	OR (95%CI)	P value
Sex
Male	1 (Reference)	-	-	-
Female	1.229 (0.568-2.660)	0.600	-	-
Age (years)
< 60	1 (Reference)	-	-	-
≥ 60	0.703 (0.277-1.786)	0.459	-	-
BMI (kg/m2)
< 24	1 (Reference)	-	-	-
≥ 24	0.592 (0.227-1.541)	0.283	-	-
Location
Right colon	1 (Reference)	-	1 (Reference)	-
Left colon	0.377 (0.138-0.914)	0.032	0.351 (0.133-0.926)	0.034
Rectum	0.624 (0.176-2.210)	0.465	0.503 (0.134-1.83)	0.308
Size (mm)
10-19	1 (Reference)	-	1 (Reference)	-
20-29	1.740 (0.653-4.639)	0.268	1.870 (0.675-5.183)	0.228
≥ 30	5.079 (1.937-13.316)	0.001	4.888 (1.708-13.989)	0.003
LST subtype
G-H	1 (Reference)	-	1 (Reference)	-
G-M	3.718 (1.055-13.103)	0.041	3.382 (0.929-12.310)	0.064
NG-F	2.571 (0.623-10.612)	0.192	3.575 (0.826-15.470)	0.088
NG-PD	3.414 (0.654-17.828)	0.145	4.990 (0.904-27.533)	0.065
Histologic grade
Low-grade dysplasia	1 (Reference)	-	-	-
High-grade dysplasia	1.928 (0.814-4.564)	0.136	-	-
Adenocarcinoma	1.672 (0.569-4.909)	0.350	-	-
Resection method
EMR	1 (Reference)	-	-	-
ESD	0.577 (0.234-1.423)	0.233	-	-
Submucosa invasion
No	1 (Reference)	-	-	-
Yes	1.534 (0.503-4.684)	0.452	-	-

BMI: Body mass index; LST: Laterally spreading tumor; G-H: Laterally spreading tumor granular homogeneous type; G-M: Laterally spreading tumor granular nodular mixed type; NG-F: Laterally spreading tumor non-granular flat elevated type; NG-PD: Laterally spreading tumor non-granular pseudo depressed type; EMR: Endoscopic mucosal resection; ESD: Endoscopic submucosal dissection; OR: Odds ratio; CI: Confidence interval.