Endoscopic resection of colorectal laterally spreading tumors: Clinicopathologic characteristics and risk factors for treatment outcomes

Table 5 Univariate and multivariate analysis of risk factors for submucosal invasion

Variables	Univariate		Multivariate
	OR (95%CI)	P value	OR (95%CI)	P value
Sex
Male	1 (Reference)	-	-	-
Female	0.656 (0.331-1.301)	0.228	-	-
Age (years)
< 60	1 (Reference)	-	-	-
≥ 60	1.158 (0.554-2.420)	0.697	-	-
BMI (kg/m2)
< 24	1 (Reference)	-	-	-
≥ 24	1.060 (0.525-2.140)	0.871	-	-
Location
Right colon	1 (Reference)	-	-	-
Left colon	0.993 (0.472-2.088)	0.985	-	-
Rectum	1.925 (0.706-4.718)	0.214	-	-
Size (mm)
10-19	1 (Reference)	-	1 (Reference)	-
20-29	2.685 (1.129-6.387)	0.025	2.631 (1.066-6.494)	0.036
≥ 30	3.415 (1.333-8.752)	0.011	3.449 (1.260-9.443)	0.016
LST subtype
G-H	1 (Reference)	-	1 (Reference)	-
G-M	1.636 (0.653-4.097)	0.293	1.363 (0.536-3.470)	0.516
NG-F	0.687 (0.194-2.433)	0.561	0.845 (0.234-3.046)	0.797
NG-PD	6.169 (2.113-18.010)	0.001	6.506 (2.180-19.420)	0.001

BMI: Body mass index; LST: Laterally spreading tumor; G-H: Laterally spreading tumor granular homogeneous type; G-M: Laterally spreading tumor granular nodular mixed type; NG-F: Laterally spreading tumor non-granular flat elevated type; NG-PD: Laterally spreading tumor non-granular pseudo depressed type; OR: Odds ratio; CI: Confidence interval.