Endoscopic resection of colorectal laterally spreading tumors: Clinicopathologic characteristics and risk factors for treatment outcomes

Table 4 Univariate and multivariate analysis of predictors for high-grade dysplasia/carcinoma

Factors	Univariate		Multivariate
	OR (95%CI)	P value	OR (95%CI)	P value
Sex
Male	1 (Reference)	-	1 (Reference)	-
Female	0.591 (0.389-0.898)	0.014	0.571 (0.367-0.889)	0.013
Age (years)
< 60	1 (Reference)	0.605	-	-
≥ 60	1.125 (0.720-1.759)	-	-	-
BMI (kg/m2)
< 24	1 (Reference)	-	-	-
≥ 24	0.916 (0.594-1.411)	0.689	-	-
Smoking
No	1 (Reference)	-	-	-
Yes	1.465 (0.911-2.356)	0.115	-	-
Alcohol drinking
No	1 (Reference)	-	-	-
Yes	1.641 (0.991-2.719)	0.054	-	-
Location
Right colon	1 (Reference)	-	-	-
Left colon	0.852 (0.545-1.331)	0.481	-	-
Rectum	1.658 (0.855-3.215)	0.135	-	-
Size (mm)
10-19 mm	1 (Reference)	-	1 (Reference)	-
20-29 mm	1.679 (1.054-2.673)	0.029	1.556 (0.953-2.542)	0.077
≥ 30 mm	2.398 (1.327-4.334)	0.004	1.934 (1.059-3.738)	0.032
LST subtype
G-H	1 (Reference)	-	1 (Reference)	-
G-M	1.914 (1.145-3.201)	0.013	2.100 (1.253-3.520)	0.005
NG-F	0.457 (0.231-0.904)	0.024	0.638 (0.315-1.292)	0.212
NG-PD	2.798 (1.238-6.323)	0.013	3.016 (1.239-7.339)	0.015

BMI: Body mass index; LST: Laterally spreading tumor; G-H: Laterally spreading tumor granular homogeneous type; G-M: Laterally spreading tumor granular nodular mixed type; NG-F: Laterally spreading tumor non-granular flat elevated type; NG-PD: Laterally spreading tumor non-granular pseudo depressed type; OR: Odds ratio; CI: Confidence interval.