Endoscopic resection of colorectal laterally spreading tumors: Clinicopathologic characteristics and risk factors for treatment outcomes

Table 2 Subgroup comparison between patients with laterally spreading tumor granular and non-granular laterally spreading tumor, n (%)

Variables	LST-G (n = 260)	LST-NG (n = 115)	χ2	P value
Gender			0.063	0.802
Male	132 (50.8)	60 (52.2)
Female	128 (49.2)	55 (47.8)
Age (years)			0.360	0.549
< 60	85 (32.7)	34 (29.6)
≥ 60	175 (67.3)	81 (70.4)
Smoking			0.971	0.324
No	200 (76.9)	32 (27.8)
Yes	60 (23.1)	83 (72.2)
Alcohol drinking			0.882	0.348
No	210 (80.8)	88 (76.5)
Yes	50 (19.2)	27 (23.5)
Location			5.642	0.060
Right colon	125 (48.1)	56 (48.7)
Left colon	98 (37.7)	52 (45.2)
Rectum	37 (14.2)	7 (6.1)
Size (mm)
10-19 mm	112 (43.1)	77 (67.0)	20.286	0.000
20-29 mm	96 (36.9)	30 (26.1)
≥ 30 mm	52 (20.0)	8 (7.0)
Histologic grade			7.491	0.024
Low-grade dysplasia	146 (56.2)	80 (69.6)
High-grade dysplasia	76 (29.2)	19 (16.5)
Adenocarcinoma	38 (14.6)	16 (13.9)
Mucosal caner	14 (5.4)	2 (1.7)
SM1 cancer	11 (4.2)	9 (7.8)
SM2 cancer	13 (5.0)	5 (4.3)
Resection method			6.760	0.009
EMR	35 (13.5)	28 (24.3)
ESD	225 (86.5)	87 (75.7)
Procedural characteristics
En bloc resection	250 (96.2)	111 (96.5)	0.030	0.862
R0 resection	242 (93.1)	108 (93.9)	0.090	0.765
Complications
Delayed bleeding	6 (2.3)	3 (2.6)	0.031	0.861
Perforation	13 (5.0)	6 (5.2)	0.008	0.929

LST-G: Laterally spreading tumor granular; LST-NG: Non-granular laterally spreading tumor; SM1: Submucosal colorectal cancer with depth of invasion in the submucosa < 1000 μm; SM2: Submucosal colorectal cancer with depth of invasion in the submucosa ≥ 1000 μm; EMR: Endoscopic mucosal resection; ESD: Endoscopic submucosal dissection.