Endoscopic resection of colorectal laterally spreading tumors: Clinicopathologic characteristics and risk factors for treatment outcomes

Table 1 Clinicopathological features of endoscopically resected laterally spreading tumors, n (%)

Variables	n = 375
Gender
Male	192 (51.2)
Female	183 (48.8)
Age (year), mean ± SD	63.25 ± 10.086 (32-88)
Smoking status (non-smoker/current or ex-smoker)	283 (75.5)/92 (24.5)
Alcohol drinking (no/yes)	298 (79.5)/77 (20.5)
BMI (kg/m2)	23.155 ± 2.885 (13.971-33.203)
Size (mm)	20.063 ± 10.078 (10-105)
Location
Cecum	25 (6.7)
Ascending colon	109 (29.1)
Transverse colon	88 (23.5)
Descending colon	37 (9.9)
Sigmoid colon	72 (19.2)
Rectum	44 (11.7)
Size (mm)
10-19 mm	189 (50.4)
20-29 mm	126 (33.6)
≥ 30 mm	60 (16.0)
Morphology
G-H	102 (27.2)
G-M	158 (42.1)
NG-F	83 (22.1)
NG-PD	32 (8.5)
Histologic grade
Low-grade dysplasia	226 (60.3)
High-grade dysplasia	95 (25.3)
Adenocarcinoma	54 (14.4)
Mucosal cancer	16 (4.3)
SM1 cancer	20 (5.3)
SM2 cancer	18 (4.8)
Resection method
EMR	63 (16.8)
ESD	312 (83.2)
Procedural characteristics
En bloc resection	361 (96.3)
R0 resection	350 (93.3)
Complications
Delayed bleeding	9 (2.4)
Minor perforation	18 (4.8)
Delayed perforation	1 (0.3)

BMI: Body mass index; LST: Laterally spreading tumor; G-H: Laterally spreading tumor granular homogeneous type; G-M: Laterally spreading tumor granular nodular mixed type; NG-F: Laterally spreading tumor non-granular flat elevated type; NG-PD: Laterally spreading tumor non-granular pseudo depressed type; SM1: Submucosal colorectal cancer with depth of invasion in the submucosa < 1000 μm; SM2: Submucosal colorectal cancer with depth of invasion in the submucosa ≥ 1000 μm; EMR: Endoscopic mucosal resection; ESD: Endoscopic submucosal dissection.