Intravenous proton pump inhibitors vs oral potassium competitive acid blockers before endoscopic treatment of bleeding peptic ulcers

doi:10.4253/wjge.v17.i6.104234

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Endosc. Jun 16, 2025; 17(6): 104234
Published online Jun 16, 2025. doi: 10.4253/wjge.v17.i6.104234

Table 3 Multivariate analysis related to rebleeding

Variables	OR	95%CI	P value
Age (year), mean ± SD	1.001	0.950-1.054	0.977
Male sex	0.804	0.153-4.216	0.797
Helicobacter pylori infection	0.624	0.151-2.584	0.515
Use of anti-coagulants	9.206	1.144-74.111	0.037^a
Use of anti-platelet	2.243	0.618-8.131	0.219
Forrest classification (≥ IIa)	1.822	0.499-6.655	0.364
PCAB (vs PPI)	0.141	0.024-0.844	0.032^a

^aStatistically significant.

CI: Confidence interval; OR: Odds ratio; PPI: Proton pump inhibitor; PCAB: Potassium competitive acid blocker.

Citation: Lim NR, Chung WC. Intravenous proton pump inhibitors vs oral potassium competitive acid blockers before endoscopic treatment of bleeding peptic ulcers. World J Gastrointest Endosc 2025; 17(6): 104234
URL: https://www.wjgnet.com/1948-5190/full/v17/i6/104234.htm
DOI: https://dx.doi.org/10.4253/wjge.v17.i6.104234