Letter to the Editor
Copyright ©The Author(s) 2025.
World J Gastrointest Endosc. May 16, 2025; 17(5): 106473
Published online May 16, 2025. doi: 10.4253/wjge.v17.i5.106473
Table 1 Summary of studies comparing early vs delayed cholecystectomy
Study ID
Number of studies
Total participants
Early CCY/delayed CCY
Relative risk for mortality
Relative risk for other findings
Length of stay (mean difference)
Gurusamy et al[7]6488244/244-Complications: RR 1.29; 95%CI: 0.61 to 2.72; Conversion: RR 0.89; 95%CI: 0.63 to 1.25; Operating time: MD -1.22 minutes; 95%CI: -3.07 to 0.64; Return to work time: MD -11.00 days; 95%CI: -19.61 to -2.39Not specified
Khan et al[9]7916455/4611.43 (0.93-2.18), I2 = 9%Biliary colic and cholecystitis: RR 9.82 (4.27-22.59), I2 = 0%; Cholangitis and recurrent jaundice: RR 2.16 (1.14-4.07), I2 = 0%MD -2.70 days (95%CI: -4.71 to -0.70)
Bagepally et al[8]3944832265/22180.74 (0.48-1.15)Pain: RR 0.38 (95%CI: 0.20-0.74); Cholangitis: RR 0.52 (95%CI: 0.28-0.97); Total biliary complications: RR 0.33 (95%CI: 0.20-0.55)MD -3.00 days (95%CI: -3.99 to -2.02)
Qi et al[10]7711332/379Not specifiedConversion rate: RR 0.38 (95%CI: 0.19 to 0.74), P = 0.005, I2 = 0%; Complications: RR 0.48 (95%CI: 0.29 to 0.79), P = 0.004, I2 = 17%; Operation time: MD -6.2 minutes (95%CI: -27.2 to -5.2), P = 0.004, I2 = 97%Not specified
CCY: Cholecystectomy; RR: Relative risk.