Impact of gut microbiome on outcomes following endoscopic interventions in gastrointestinal disease

Table 4 Colorectal Interventions

Ref.	Title	Study group	Intervention	Inference
Ben Izhak et al[48]	Projection of gut microbiome pre-and post-bariatric surgery to predict surgery outcome	Patients undergoing bariatric surgery	Bariatric surgery with perioperative microbiome profiling	Microbial shifts post-surgery correlate with weight loss success and metabolic improvements
Carlini et al[49]	Implementation of the gut microbiota prevents anastomotic leaks in laparoscopic colorectal surgery for cancer	Colorectal cancer patients undergoing laparoscopic surgery	Preoperative gut microbiota modulation	Microbiota-targeted intervention reduces anastomotic leak rates
Jin et al[50]	Gut microbiota from non-complicated anastomotic leak patients promotes colon anastomotic healing	Patients with and without anastomotic leak	Microbiota transfer from non-leak patients to epithelial cells	Microbiota from healthy patients induces collagen synthesis, promoting healing
Liu et al[51]	Improvement effect of Bifidobacterium animalis subsp. lactis MH-02 in patients receiving resection of colorectal polyps	Patients undergoing colorectal polyp resection	Bifidobacterium animalis supplementation	Probiotic improves postoperative immune parameters and recovery
Park et al[52]	Effects of probiotics on the symptoms and surgical outcomes after anterior resection of colon cancer	Colon cancer patients post anterior resection	Probiotic supplementation	Probiotics reduce postoperative symptoms and complications
Martínez-Sánchez et al[53]	Gut microbiome modification through dietary intervention in patients with colorectal cancer (protocol)	Colorectal cancer patients planned for surgery	Dietary intervention to modify microbiome	Protocol to assess dietary impact on microbiome and surgical outcomes
Veziant et al[54]	Prognostic value of combination of gut microbiota, sarcopenia, obesity, metabolic syndrome to predict surgical/oncologic outcomes in colorectal cancer	Colorectal cancer surgery patients	Observational with microbiota and clinical/metabolic factor assessment	Protocol to evaluate gut microbiota with clinical/metabolic factors for outcome prediction