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Systematic Reviews
©The Author(s) 2025.
World J Gastrointest Endosc. Nov 16, 2025; 17(11): 110082
Published online Nov 16, 2025. doi: 10.4253/wjge.v17.i11.110082
Table 1 Summary of key studies on polypectomy in ulcerative colitis
Ref.
Patients (n)
Lesion type
Polypectomy outcome
Cancer risk post-polypectomy
Recommendation
Rubin et al[5], 199948Dysplastic polyps in UC48% developed new polyps; no flat dysplasia or cancer in follow-up2% (1 case within polyp)Polypectomy with surveillance
Odze et al[6], 200434Adenoma-like DALM62.5% recurred; 1 case of adenocarcinomaAbout 3%Polypectomy if lesion well-circumscribed
Vieth et al[7], 2006148Sporadic adenomas4.6% had distant neoplasia; 2.3% carcinoma2.3%Adequate if followed by endoscopic monitoring
Engelsgjerd et al[9], 1999Case seriesAdenoma-like DALMsSimilar profile to sporadic adenomasMinimalSupports conservative management
Kisiel et al[8], 201277Polypoid dysplasia13% developed cancer/flat dysplasia13% over 5 yearsRequires close follow-up
Schaus et al[10], 200723Ileal pouch polyps91.3% inflammatory; 8.7% dysplastic/malignant8.7%Polypectomy + symptom monitoring


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