Endoscopic bariatrics: Current status and emerging technologies

Table 4 Estimated weight loss

Endoscopic bariatric techniques
Fluid-filled intragastric balloons
Orbera/BIB	34%-42% EWL at 6 months
Silimed gastric balloon	8 kg after 6 months
MedSil intragastric balloon	19% EWL at 6 months
Spatz adjustable balloon system	46% EWL at 12 months
ReShape dual intragastric balloon system	25% EWL at 6 months
Air/gas-filled intragastric balloons
Heliosphere BAG balloon	18% EWL at 6 months
Obalon gastric balloon	5 kg after 12 weeks
Ullorex oral intragastric balloon	1.5 kg over 2 weeks
Other space-occupying devices
SAB	6.5 kg after 4 months
TPS	25% EWL at 3 months 41% EWL at 6 months
SatiSphere	18.4 kg after 3 months
Gelesis100	29% EWL after 24 weeks
Suturing/stapling procedures
EndoCinch suturing system	40% EWL at 3 months 58% EWL at 12 months
Restore suturing system	28% EWL at 12 months
Overstitch endoscopic suturing system	30% EWL at 6 months 55% EWL at 12 months
TOGA	25%-46% EWL at 6 months 39% EWL at 12 months
TERIS	30% EWL at 6 months POSE 45% EWL at 12 months
Endomina suturing system	29% EWL at 12 months
Malabsorptive endoscopic weight loss procedures DJBS	12-24% EWL at 3 months 32% EWL at 6 months
Gastroduodenal-DJBS months 54% EWL	40% EWL at 3 at 12 months
Other endoscopic weight loss procedures
DMR	2.5 kg after 24 weeks Incisionless magnetic anastomosis system 40% EWL at 12 months
Intragastric injections of botulinum toxin A	11 kg after 2 months V-BLOC 17% EWL at 12 months
GES	5 kg after 6 months Gastric aspiration therapy/AspireAssist 41% EWL at 6 months 50% EWL at 12 months

Values extrapolated from representative reviews and clinical trials of each intervention. BIB: BioEnterics intragastric balloon; SAB: Semi-stationary antral balloon; TPS: TransPyloric shuttle; TOGA: Transoral gastroplasty; TERIS: Trans-oral endoscopic restrictive implant system; DJBS: Duodenaljejunal bypass sleeve; EWL: Excess weight loss; DMR: Duodenal mucosal resurfacing; GES: Gastric electrical stimulation; POSE: Primary obesity surgery endoluminal; V-BLOC: Vagal blockade.