Risk scoring system combined with traditional Chinese medicine constitution identification improves colorectal advanced neoplasms screening effectiveness for early colonoscopy

doi:10.4253/wjge.v17.i10.108929

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Endosc. Oct 16, 2025; 17(10): 108929
Published online Oct 16, 2025. doi: 10.4253/wjge.v17.i10.108929

Table 6 Diagnostic performance of the various tests or algorithms

Characteristics	AA (95%CI)			Cancer (95%CI)			AA + cancer (95%CI)
Characteristics	SEN %	SPE %	PPV %	SEN %	SPE %	PPV %	SEN %	SPE %	PPV %
APCS	49.2 (40.5-57.9)	81.4 (79.3-83.5)	20.3 (15.8-24.8)	72.7 (46.4-99.0)	79.1 (77.0-81.2)	2.6 (0.8-4.4)	51.1 (42.7-59.5)	81.8 (79.7-83.9)	23 (18.2-27.7)
APCS plus class 1 +	61.9^a (53.4-70.4)	77.5 (75.2-79.7)	21 (16.8-25.1)	81.8 (59.0-104.6)	74.4 (72.1-76.7)	2.4 (0.9-4.0)	63.5^a (55.4-71.6)	78 (75.7-80.2)	23.4 (19.1-27.7)
APCS plus class 2 +	72.2^b (64.4-80.0)	72.3 (69.9-74.7)	20.1 (16.4-23.8)	90.9 (73.9-107.9)	68.9 (66.4-71.3)	2.2 (0.9-3.6)	73.7^b (66.4-81.1)	72.9 (70.4-75.3)	22.3 (18.5-26.2)

^aP < 0.05.

^bP < 0.001.

The P value of sensitivity was compared with Asia-Pacific Colorectal Screening and Asia-Pacific Colorectal Screening plus. APCS: Asia-Pacific Colorectal Screening; AA: Advanced adenoma; SEN: Sensitivity; SPE: Specificity; PPV: Positive predictive value; CI: Confidence interval.

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Citation: Liu QH, Hou Y, Li S, Gu YL, Huang CX, Kang Q, Fan YJ, Zhu LQ, Sun L, Men RC, Li XY, Wang H, Wei XY, Sun ZG, He YQ. Risk scoring system combined with traditional Chinese medicine constitution identification improves colorectal advanced neoplasms screening effectiveness for early colonoscopy. World J Gastrointest Endosc 2025; 17(10): 108929
URL: https://www.wjgnet.com/1948-5190/full/v17/i10/108929.htm
DOI: https://dx.doi.org/10.4253/wjge.v17.i10.108929

Liu QH, Hou Y, Li S, Gu YL, Huang CX, Kang Q, Fan YJ, Zhu LQ, Sun L, Men RC, Li XY, Wang H, Wei XY, Sun ZG, He YQ. Risk scoring system combined with traditional Chinese medicine constitution identification improves colorectal advanced neoplasms screening effectiveness for early colonoscopy. World J Gastrointest Endosc 2025; 17(10): 108929 [PMID: 41181532 DOI: 10.4253/wjge.v17.i10.108929]

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