Retrospective analysis of discordant results between histology and other clinical diagnostic tests on helicobacter pylori infection

Table 6 Discrepant cases with negative histology but positive rapid urease test or stool antigen test

Cases #	No. of biopsy specimens	Histology test results		Clinical tests		Treated for H. pylori
		WS/IHC	On PPI/Antibiotics when biopsied	Pos. Clinical Tested	On PPI/Antibiotics when tested
1	3	Neg/Neg	NA	CLO	NA	Yes
2	2	Neg/Neg	NA	CLO	NA	Yes
3	3	Neg/Neg	NA	CLO	NA	NA
4	2	Neg/Neg	NA	CLO	NA	NA
5	2	Neg/Pos	No	CLO	No	No
6	2	Neg/Neg	Yes1	SA	Yes1	Yes
7	1	Neg/Neg	No	SA	Yes1	Yes
8	M	NP/Neg	Yes2	SA	No	Yes
9	3	Neg/Neg	Yes2	SA	No	Yes
10	M	Neg/Pos	Yes1	SA	Yes1	Yes
11	4	Neg/Pos	Yes1	SA	Yes1	Yes
12	3	NP/Neg	No	SA	No	No
13	M	Neg/Neg	Yes1	SA	No	No
14	2	NP/Neg	Yes1	SA	No	Yes
15	1	NP/Neg	Yes2	SA	No	Yes
16	2	Neg/Pos	Yes1	SA	No	Yes

¹PPI only.

²PPI and antibiotics.

WS: Warthin-Starry stain; IHC: Immunohistochemistry; H. pylori: Helicobacter pylori; CLO: Campylobacter-like organism (rapid urease test); SA: Stool antigen test; PPI: Proton pump inhibitor; NA: Not available; Neg: Negative; Pos: Positive; M: Multiple (6 fragments and up).