Efficacy and tolerability of high and low-volume bowel preparation compared: A real-life single-blinded large-population study

Table 1 Demographic and clinical features of the study population, n (%)

Characteristics	High volume (n = 871)	Low volume (n = 944)	P value1
Age	61.2 ± 14.3	60.1 ± 14.6	0.092
Male sex	463 (53.2)	448 (47.5)	0.0153
Split-dose	389 (44.7)	361 (38.2)	0.0063
High-definition colonoscope	296 (33.9)	310 (32.8)	0.605
Indication
Symptoms	538 (61.8)	563 (59.6)
Surveillance			< 0.0013
Post polypectomy	134 (15.4)	154 (16.3)
Post colonic resection for CRC	73 (8.4)	73 (7.7)
Positive FBT	94 (10.8)	57 (6.1)
IBD	32 (3.6)	97 (10.3)
BMI, mean ± SD2	25.5 ± 4.3	25.0 ± 4.0	0.0153
Previous abdominal surgery	98 (11.3)	96 (10.2)	0.456
Constipation	66 (7.6)	86 (9.1)	0.239
Comorbidities
Heart disease	90 (10.3)	65 (6.9)	0.0093
Diabetes	72 (8.3)	65 (6.9)	0.266
Stroke/dementia	19 (2.2)	25 (2.6)	0.518
Severe CKD	21 (2.4)	15 (1.6)	0.209
Cirrhosis	12 (1.4)	13 (1.4)	0.999
GERD	192 (22.0)	219 (23.2)	0.557
Waiting time > 1 mo	485 (55.7)	570 (60.4)	0.0903
Non-adherence to low fiber diet	91 (10.5)	112 (11.9)	0.329
Lives alone2	123 (14.8)	149 (16.3)	0.395
Low instruction2	157 (19.6)	122 (14.1)	0.0023

¹P value degrees of freedom = 1, except for age (1814), indication (4) and body mass index (BMI) (1726).

²BMI available for 1727 patients; information about living alone available for 1747 patients; instruction level available for 1662 patients.

³Significant different.

CRC: Colorectal cancer; FBT: Fecal blood test; IBD: Inflammatory bowel disease; BMI: Body mass index; CKD: Chronic kidney disease; GERD: Gastroesophageal reflux disease.