Copyright
©The Author(s) 2021.
World J Gastrointest Endosc. Jan 16, 2021; 13(1): 1-12
Published online Jan 16, 2021. doi: 10.4253/wjge.v13.i1.1
Published online Jan 16, 2021. doi: 10.4253/wjge.v13.i1.1
Table 2 The common forms of systemic amyloidosis with organ involvement
| Type of systemic amyloidosis | Causative protein | Organ involvement |
| Primary systemic amyloidosis | Monoclonal light chain (AL) | Heart, Kidneys, Liver, Peripheral nervous system, Autonomic nervous system, and Gastrointestinal tract |
| Senile systemic amyloidosis | Wild-type transthyretin (ATTR) | Heart |
| Hereditary systemic amyloidosis | Mutant transthyretin (ATTR); Apolipoprotein 1 (AApoA1); Mutant fibrinogen A alpha (AFib); Lysozyme (ALys) | Heart; Heart, Kidneys, Liver, Peripheral nervous system, and Skin; Kidneys and Liver; Kidneys and Liver |
| Isolated Atrial Systemic Amyloidosis | Atrial natriuretic factor (AANF) | Heart |
| Secondary Systemic Amyloidosis | Serum amyloid A (AA) | Kidneys, Heart, and Gastrointestinal tract |
| Dialysis-Related Systemic Amyloidosis | β2-microglobulin (Aβ2M) | Osteoarticular tissue, Circulatory system, and Gastrointestinal tract |
| Finnish-type Systemic Amyloidosis | Gelsolin (AGel) | Lattice dystrophy of cornea, and Corneal neuropathy |
- Citation: Dahiya DS, Kichloo A, Singh J, Albosta M, Wani F. Gastrointestinal amyloidosis: A focused review. World J Gastrointest Endosc 2021; 13(1): 1-12
- URL: https://www.wjgnet.com/1948-5190/full/v13/i1/1.htm
- DOI: https://dx.doi.org/10.4253/wjge.v13.i1.1