Role of endoscopy in the management of primary sclerosing cholangitis

Figure 2 Example of the use of chromoendoscopy in a patient with primary sclerosing cholangitis. In this example, the colon was irrigated using a methylene blue solution. Targeted biopsies were obtained in a region of the sigmoid colon where decreased uptake of methylene blue revealed a diffusely flat, nodular region. Pathology revealed multifocal low-grade dysplasia requiring total proctocolectomy.