Propofol vs traditional sedatives for sedation in endoscopy: A systematic review and meta-analysis

Table 1 Characteristics of the studies included in the meta-analysis

Author	Ref.	Country	Year	Patients (n = 3854)	Interven-tion	Interven-tion (n = 1834)	Control	Control (n = 2004)	Procedure	Jadad
Seifert	[19]	Germany	2000	239	PROP	120	PROP + MDZ	119	Endoscopy/ERCP	5
Sipe	[39]	USA	2002	80	PROP	40	MDZ + MEP	40	Colono-scopy	4
Vargo	[35]	USA	2002	75	PROP	38	MDZ + MEP	37	ERCP/EUS	4
Ulmer	[40]	USA	2003	100	PROP	50	MDZ + FTN	50	Colono-scopy	4
Riphaus	[41]	Germany	2005	150	PROP	75	MDZ + MEP	75	ERCP	5
VanNatta	[12]	USA	2006	200	PROP	50	FTN + PROP/MDZ + PROP/MDZ + FTN + PROP	150	Colono-scopy	3
Fanti	[42]	Italy	2007	270	PROP	135	PROP + MDZ	135	EUS	5
Dewitt	[44]	USA	2008	80	PROP	40	MDZ + MEP	40	EUS	5
Kongkam	[43]	Thailand	2008	134	PROP	67	MDZ + MEP	67	ERCP	4
Schilling	[45]	Germany	2009	150	PROP	75	MDZ + MEP	75	ERCP/EUS/Enteroscopy	5
Pascual	[26]	Cuba	2011	512	PROP	256	MDZ + MEP	256	Colono-scopy	4
Lee	[25]	Korea	2011	222	PROP + MDZ + MEP	102	MDZ + MEP	104	Endoscopy/ERCP	5
Chun	[31]	Korea	2012	135	PROP	67	PROP + MDZ	68	Stomach ESD	3
Angsuwatcharakon	[30]	Thailand	2012	205	PROP + MDZ + MEP	103	MDZ + MEP	102	ERCP	3
Lee	[29]	Korea	2012	206	PROP	104	PROP + MDZ + FTN	102	ERCP/EUS	5
Zuo	[28]	China	2012	100	PROP	49	MDZ + FTN	51	Endomicroscopy	5
Levitzky	[27]	USA	2012	110	PROP + MDZ + FTN	55	MDZ + FTN	55	Endoscopy	3
Gurbulak	[33]	Turkey	2014	124	PROP	62	MDZ + MEP	62	Colono-scopy	5
Chan	[32]	Taiwan	2014	220	PROP	110	PROP + MDZ + AFTN	110	Endoscopy + colonoscopy	5
Hsu	[36]	Taiwan	2015	100	PROP	50	PROP + MDZ +FTN	50	Endoscopy + colonoscopy	1
Haytural	[34]	Turkey	2015	90	PROP	30	PROP + FTN/PROP + RFTN	60	ERCP	1
Li	[38]	China	2016	90	PROP	30	PROP + FTN	60	Colono-scopy	3
Schroeder	[37]	USA	2016	262	PROP	126	MDZ + FTN	136	Colono-scopy	4

MDZ: Midazolam; FTN: Fentanyl; PROP: Propofol; MEP: Meperidine; RFTN: Remifentanil; AFTN: Alfentanil.