胃黏膜上皮内瘤变患者653例的临床病理特点分析

表1 653例GIN患者的一般特征、内镜下表现及病理特点

	LGIN (536例)	HGIN (117例)	χ2	P值
性别			1.082	0.298
男	363 (55.59%)	85 (13.02%)
女	173 (26.49%)	32 (4.90%)
年龄a			22.537	<0.001
<49	93 (14.24%)	6 (0.92%)
49-59	177 (27.11%)	32 (4.90%)
≥60	266 (40.74%)	85 (13.02%)
病变部位a			29.562	<0.001
胃角	57 (10.63%)	14 (11.97%)
胃体	14 (2.61%)	14 (11.97%)
胃窦	332(61.94%)	49 (41.88%)
多部位	133(24.81%)	40 (34.19%)
病变分型			2.241	0.134
0-Ⅱa	452 (84.33%)	92 (78.63%)
其它0型病变	84 (15.67%)	25 (21.37%)
病变大小a			68.673	<0.001
<1 cm	294 (54.85%)	15 (12.82%)
1 cm-2 cm	186 (34.70%)	75 (64.10%)
>2 cm	56 (10.45%)	27 (23.08%)
萎缩a			16.968	<0.001
萎缩	396 (73.88%)	64 (54.70%)
非萎缩	140 (26.12%)	53 (45.30%)
肠化a			41.509	<0.001
肠化	428 (79.85%)	60 (51.28%)
非肠化	108 (20.15%)	57 (48.72%)
H. pylori			1.959	0.162
阳性	140 (26.12%)	38 (32.48%)
阴性	396 (73.88%)	79 (67.52%)

LGIN组 vs HGIN组,

^aP<0.05. GIN: 胃黏膜上皮内瘤变; LGIN: 胃黏膜低级别上皮内瘤变; HGIN: 胃黏膜高级别上皮内瘤变. H. pylori: 幽门螺杆菌.