靶向肠道菌群治疗胃肠疾病研究进展

表1 与胃肠疾病相关的肠道菌群组成变化

疾病	与疾病相关的物种丰度变化		Ref.
	减少	增加
肠易激综合征	Bifidobacterium, Faecalibacterium, Uncultured Clostridiales I	Lactobacillaceae, Bacteroides, Enterobacteriaceae	[10]
		Veillonella, Lactobacillus	[12]
	Lachnobacterium, Prevotella, Catenibacterium	Blautia, Bacteroides, Ruminoccocus, unknown Barnesiellaceae	[13]
溃疡性结肠炎		Fusobacterium nucleatum	[18]
	Roseburia		[21]
克罗恩病		Ruminococcus gnavus	[19]
	Faecalibacterium, Roseburia		[20]
结直肠癌		Bacteroides fragilis, Fusobacterium nucleatum, Porphyromonas asaccharolytica, Parvimonas micra, Prevotella intermedia, Alistipes finegoldii, Thermanaerovibrio acidaminovorans	[23]
		Fusobacterium nucleatum spp., Atopobium parvulum, Actinomyces odontolyticus	[24]
		Bacteroides fragilis	[25]
		pks+ E. coli	[26]
		Peptostreptococcus anaerobius	[28]