EIF3h、MMP-10和MMP-11在结肠腺癌中的表达及意义

表2 都EIF3h、MMP-10和MMP-11在观察组不同临床特征中的表达 n (%)

临床特征	n	EIF3h		χ2	P	MMP-10		χ2	P	MMP-11		χ2	P
		+	-			+	-			+	-
淋巴结转移
无	76	28 (36.8)	48 (63.2)	10.733	0.001	28 (36.8)	48 (63.2)	5.907	0.015	34 (44.7)	42 (55.3)	4.938	0.026
有	34	24 (70.6)	10 (29.4)			21 (61.8)	13 (38.2)			23 (67.6)	11 (32.4)
分化程度
高-中	84	32 (38.1)	52 (61.9)	12.009	0.001	39 (46.4)	45 (53.6)	0.510	0.475	45 (53.6)	39 (46.4)	0.438	0.508
低	26	20 (76.9)	6 (23.1)			10 (38.5)	16 (61.5)			12 (46.2)	14 (53.8)
最大径
<5 cm	43	10 (23.3)	33 (76.7)	16.337	0.000	19 (44.2)	24 (55.8)	0.004	0.952	27 (62.8)	16 (37.2)	3.404	0.065
≥5 cm	67	42 (62.7)	25 (37.3)			30 (44.8)	37 (55.2)			30 (44.8)	37 (55.2)
脉管侵犯
无	88	42 (47.7)	46 (52.3)	0.036	0.849	34 (38.6)	54 (61.4)	9.219	0.013	41 (46.6)	47 (53.4)	4.815	0.028
有	22	10 (45.5)	12 (54.5)			15 (68.2)	7 (31.8)			16 (72.7)	6 (27.3)
性别
男	57	22 (38.6)	35 (61.4)	3.573	0.059	26 (45.6)	31 (54.4)	0.055	0.815	29 (50.9)	28 (49.1)	0.042	0.838
女	53	30 (56.6)	23 (43.4)			23 (43.4)	30 (56.6)			28 (52.8)	25 (47.2)
年龄
<60	40	22 (55.0)	18 (45.0)	1.506	0.220	14 (35.0)	26 (65.0)	2.319	0.128	25 (62.5)	15 (37.5)	2.873	0.090
≥60	70	30 (42.9)	40 (57.1)			35 (50.0)	35 (50.0)			32 (45.7)	38 (54.3)
炎细胞浸润
轻	64	27 (42.2)	37 (57.8)	1.588	0.208	29 (45.3)	35 (54.7)	0.036	0.849	36 (56.3)	28 (43.8)	1.204	0.273
重	46	25 (54.3)	21 (45.7)			20 (43.5)	26 (56.5)			21 (45.7)	25 (54.3)
增殖指数
<50%	43	14 (32.6)	29 (7.4)	6.491	0.011	19 (44.2)	24 (55.8)	0.004	0.952	25 (58.1)	18 (41.9)	1.130	0.288
≥50%	67	38 (57.4)	29 (42.6)			30 (44.8)	37 (55.2)			32 (47.8)	35 (52.2)
TNM分期
Ⅰ+Ⅱ期	81	32 (39.5)	49 (60.5)	7.435	0.006	33 (40.7)	48 (59.3)	1.800	0.180	40 (49.4)	41 (50.6)	0.730	0.393
Ⅲ+Ⅳ期	29	20 (69.0)	9 (31.0)			16 (55.2)	13 (44.8)			17 (58.6)	12 (41.4)

EIF3h: 真核翻译起始因子3h; MMP-10: 基质金属蛋白酶-10; MMP-11: 基质金属蛋白酶-11.