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©The Author(s) 2015.
世界华人消化杂志. 2015-01-08; 23(1): 147-152
在线出版 2015-01-08. doi: 10.11569/wcjd.v23.i1.147
在线出版 2015-01-08. doi: 10.11569/wcjd.v23.i1.147
表2 血浆miR-210、CA199、CA242、CEA及联合在各组间的诊断效能
| 分组 | 敏感性(%) | 特异性(%) | 准确性(%) | LR+ | LR- |
| 胰腺癌组 vs 正常组 | |||||
| miR-210 | 96.7 | 50.0 | 90.0 | 1.93 | 0.07 |
| CA199 | 91.7 | 30.0 | 82.9 | 1.31 | 0.28 |
| CA242 | 98.3 | 10.0 | 85.7 | 1.09 | 0.17 |
| CEA | 100.0 | 0.0 | 85.7 | -- | -- |
| CA199+CA242+CEA | 93.3 | 30.0 | 84.3 | 1.33 | 0.22 |
| miR-210+CA199 | 96.7 | 70.0 | 92.9 | 3.22 | 0.05 |
| miR-210+CA199+CA242+CEA | 96.7 | 70.0 | 92.9 | 3.22 | 0.05 |
| 胰腺癌组 vs 慢性胰腺炎组 | |||||
| miR-210 | 95.0 | 25.0 | 77.5 | 1.14 | 0.22 |
| CA199 | 81.7 | 80.0 | 81.3 | 4.08 | 0.23 |
| CA242 | 85.0 | 30.0 | 71.3 | 1.21 | 0.50 |
| CEA | 100.0 | 0.0 | 75.0 | -- | -- |
| CA199+CA242+CEA | 81.7 | 75.0 | 80.0 | 3.27 | 0.24 |
| miR-210+CA199 | 90.0 | 85.0 | 88.8 | 6.00 | 0.12 |
| miR-210+CA199+CA242+CEA | 90.0 | 85.0 | 88.8 | 6.00 | 0.12 |
| 胰腺癌组 vs 慢性胰腺炎组+正常组 | |||||
| miR-210 | 86.7 | 40.0 | 71.1 | 1.44 | 0.33 |
| CA199 | 78.3 | 93.3 | 83.3 | 11.75 | 0.23 |
| CA242 | 76.7 | 83.3 | 78.9 | 4.60 | 0.28 |
| CEA | 98.3 | 10.0 | 68.9 | 1.09 | 0.17 |
| CA199+CA242+CEA | 80.0 | 93.3 | 84.4 | 12.00 | 0.21 |
| miR-210+CA199 | 88.3 | 90.0 | 88.9 | 8.83 | 0.13 |
| miR-210+CA199+CA242+CEA | 86.7 | 90.0 | 87.8 | 8.67 | 0.15 |
引文著录: 胡应霞, 张海蓉, 石围, 唐君瑞. 血浆miR-210联合血清肿瘤标志物对胰腺癌的诊断价值. 世界华人消化杂志 2015; 23(1): 147-152