SELDI-TOF-MS联合LCM技术筛选大肠癌肝转移早期诊断标志蛋白

表2 大肠癌肝转移灶与原发灶癌细胞之间差异蛋白数据库搜索结果

差异蛋白质(Da)	Swiss-Prot 代码	等电点	分子量(Da)	蛋白质名称
4676.63	Q07812-3	11.22	4678	Apoptosis regulator Bax (Isoform Gamma)
5914.77	P05067	7.01	5911	Gamma-secretase C-terminal fragment 50
6027.30	Q13794	10.31	6030	PMA-induced protein 1
	P02776	10.03	6033	Platelet factor 4 precursor
7573.24	O60671-3	6.00	7576	Cell cycle checkpoint protein RAD1 (Isoform 3)
	P53634	4.76	7578	Dipeptidyl peptidase 1 light chain
9296.24	P02775	7.85	9292	Connective tissue-activating peptide III
	Q9NQW1	6.55	9294	SEC31-related protein B (Isoform 3)
11740.87	P31949	6.55	11741	Protein S100-A11
13881.46	Q9Y5J5	9.72	13891	Pleckstrin homology-like domain family A member 3
21063.59	P30086	7.43	21057	Raf kinase inhibitor protein(RKIP)
22783.36	P40198-3	5.97	22783	Heat shock protein 27(HSP-27)