蛋白芯片技术对肝细胞癌组织蛋白谱的建立及标志蛋白的筛选

表2 SWISS-PROT数据库中检索的人HCC肝组织差异蛋白(肽段)

分子量(Da)	检索结果
	Anaphase-promoting complex subunit 11
	(Q9NYG5)
	Cyclin-dependent kinases regulatory sub-
	unit 2 (P33552)
	Pro-MCH-like protein 2 (Q9BQD1)
	Protein transport protein Sec61 subunit
	beta (P60468)
9846.428	Caspase-9 subunit p10 (P55211)
4674.091	Bax protein, cytoplasmic isoform gamma
	(Q07815)
7219.294	Platelet basic protein precursor (P02775)
	Cholecystokinins precursor (P06307)
	NADH-ubiquinone oxidoreductase chain 4L
	(P03901)
10747.82	Protein S100-A5 (P33763)
31748.55	Nit protein 2 (Q86X76)
	S-adenosylmethionine decarboxylase
	proenzyme (P17707)
7678.362	Platelet factor 4 variant precursor (P10720)
2641.05	Endothelin-3 precursor (P14138)
31037.76	enoyl-coenzyme A hydratase 1, short-
	chain (Q58EZ5)
	vascular endothelial growth factor (VEGF)
	isoform
15137.76	Growth/differentiation factor 9 precursor
	(O60383)
	Beta-glucuronidase-like protein 1
	(Q9NQQ0)
	Interleukin-2 precursor (P09105)
15341.82	Interleukin-2 precursor (P60568)
7576.037	Dipeptidyl-peptidase 1 precursor (P53634)
4524.928	Orexigenic neuropeptide QRFP precursor
	(P83859)
	Beta-defensin 107A precursor (Q8IZN7)
4974.046	Gastric inhibitory polypeptide precursor
	(P09681)
2273.905	Prolactin-releasing peptide precursor
	(P81277)
	Guanine nucleotide-binding protein G(I)/
	G(S)/G(O) gamma-T2 subunit precursor
	(O14610)
7431.591	Growth-regulated protein alpha precursor
	(P09341)
	Cytochrome c oxidase polypeptide VIIa-
	heart, mitochondrial precursor (P24310)
6758.022	WAP four-disulfide core domain protein
	10A precursor (Q9H1F0)

括号内为蛋白分子在ExPasy数据库中的编号.