外源质粒DNA对小鼠肠道基因表达谱的影响

表2 质粒灌胃后4 h肠道中表达下调的基因

GenBank accession	Cy5/Cy3	Symbol	基因名称
X78543	0.0829	MCPT-PS1	肥大细胞蛋白酶
NM_008339	0.1468	CD79B	免疫球蛋白基因
AK008016	0.1705	2010001M09RIK	RIKEN cDNA 2010001M09 gene
NM_009696	0.2125	APOE	Apolipoprotein E载脂蛋白E
NM_011402	0.2243	SLC34A2	Solute carrier family 34 (sodium phosphate), member 2溶质载体家族
NM_013492	0.2466	CLU	Clusterin簇集蛋白
NM_007398	0.2932	ADA	Adenosine deaminase腺苷脱氨酶
NM_010382	0.2964	H2-EB1	Histocompatibility 2, class II antigen E beta主要组织相容性抗原基因II
NM_007489	0.3206	ARNTL	Aryl hydrocarbon receptor nuclear translocator-like芳烃受体核移位因子
NM_009042	0.3611	REG1	Regenerating islet-derived 1 再生基因
BC021548	0.3644	0610039P13RIK	RIKEN cDNA 0610039P13 gene
AY030094	0.3734	4932416A11RIK	Mus musculus von Willebrand factor A-related protein (Warp) mRNA, complete cds
NM_011468	0.376	SPRR2A	富含脯氨酸小蛋白
AK004658	0.39	HSPCA	热休克蛋白86
BC007144	0.4201	PSCDBP	Expressed sequence C80816
NM_021520	0.4247	SLC28A2	溶质载体家族28
NM_019411	0.425	PPP2CA	蛋白磷酸酯酶
BC011492	0.4303	9130020G10RIK	RIKEN cDNA 9130020G10 gene
M28739	0.4349	TUBB2	Tubulin, beta 2 微管蛋白
NM_009825	0.4648	SERPINH1	热休克蛋白47
NM_130450	0.4711	ELOVL6	Expressed sequence C77826
NM_009810	0.4712	CASP3	Caspase 3, apoptosis related cysteine protease
NM_009984	0.4725	CTSL	组织蛋白酶
NM_023114	0.4757	APOC3	Apolipoprotein CIII载脂蛋白C III