Copyright ©The Author(s) 2020.
World J Meta-Anal. Apr 28, 2020; 8(2): 54-66
Published online Apr 28, 2020. doi: 10.13105/wjma.v8.i2.54
Table 1 Treatments used in inflammatory bowel disease and their side effects
ClassesAdverse effectsRef.
AminosalicylatesMesalazine-nephrotoxicity and pancreatitis; sulfasalazine-blood dyscrasias[10,11]
AntibioticsPhotosensitivity, tendonitis, tendon rupture, cartilage growth inhibition in fetuses and children oral candidiasis, gastrointestinal disorders, peripheral neuropathy[14-16]
CorticosteroidsAcne, moon face and edema, sleep and mood disorders. Posterior subcapsular cataract, osteoporosis, myopathy, and susceptibility to infection. Acute adrenal insufficiency, arthralgia, increased intracranial pressure and pseudo-rheumatism syndrome[7,20-22]
ThiopurineHepatotoxicity, gastric intolerance and pancreatitis[32]
MethotrexateNausea, vomiting and diarrhea[34]