Case Report
Copyright ©The Author(s) 2020.
World J Clin Cases. Feb 6, 2020; 8(3): 606-613
Published online Feb 6, 2020. doi: 10.12998/wjcc.v8.i3.606
Table 1 Clinical and histopathologic characteristics of prostatic stromal sarcoma with rhabdoid features
Ref.Age in yrClinical presentationPattern of H and EPattern of IHTreatmentOutcome
Yokota et al[4]45Hematuria, dysuria, episodes of intermittent feverStriking proliferation of undifferentiated cells of mesenchymal type with round and spindle-shaped nuclei were shown in the stroma; PAS stain was positivePSA (+)ColostomyRecurrence with death 4 mo after surgery
De Raeve et al[1]36Recurrent urinary obstructionPhyllodes, cystically dilated ducts; Spindle-shaped tumor cells; Fascicularis, mitotic figures (more than 38/10 HPF); Well-differentiated rhabdomyoblastsRhabdomyoblastic cells: muscle specific actin (+), desmin (+), myoD1 (+); Stromal tumor cells: Ki-67 (+), CD34 (-), α-SMA (-), desmin (-), actin (-)Prostatectomy followed by chemotherapy and radiotherapyRecurrence after prostatectomy 4 mo later
Herawi et al[3]N/AN/AFocal rhabdomyosarcomatous differentiationRhabdomyoblastic cells: desmin (+), myogenin (+)N/AN/A
Kim et al[2]31Voiding difficulty and anal painBiphasic growth pattern with spindle and epithelioid cells, highly cellular spindle tumor cells with focal nuclear pleomorphism; Focal cells with rhabdoid featuresSpindle cells and epithelioid tumor cells: vimentin (+), CD34 (+), progesterone receptors (+), INI1 (+); Rhabdoid cells: INI1 (+)Radical prostatectomy followed by cystectomyRecurrence, with death 3 mo after cystectomy
Current case34Hematuria and progressive dysuriaHuge number of atypia spindle cells; Poor differentiation of embryonoid rhabdomyoblasts with abundant eosinophilic cytoplasmSpindle cells: vimentin (+), β-catenin (+); Rhabdomyoblastic cells: MyoD1 (+), myogenin (+) INI1 (+); Epithelioid cells: PSA (+)Transurethral prostatectomyDied of uncontrollable tumor and severe bleeding 3 mo after surgery