Case Report
Copyright ©The Author(s) 2023.
World J Clin Cases. May 16, 2023; 11(14): 3288-3294
Published online May 16, 2023. doi: 10.12998/wjcc.v11.i14.3288
Figure 1
Figure 1 Pedigree of the patient and mutation analysis of the SPG4 gene. A: The family with hereditary spastic paraplegia (HSP). The proband is indicated by an arrow. A square indicates male, a circle for female, a shadow symbol for an HSP individual, including a black shadow for a symptomatic patient and a gray shadow for an asymptomatic patient, a non-shadowing symbol for a non-HSP individual, and a slash symbol for a deceased individual; B: Sequence analysis identified a c. 1053dupA mutation in the SPG4 gene in this family. Black frames delineate the C. 1053dupA nucleotides; and C: Wild-type sequence.