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For: Osborn O, Oh DY, McNelis J, Sanchez-Alavez M, Talukdar S, Lu M, Li P, Thiede L, Morinaga H, Kim JJ, Heinrichsdorff J, Nalbandian S, Ofrecio JM, Scadeng M, Schenk S, Hadcock J, Bartfai T, Olefsky JM. G protein-coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice. J Clin Invest. 2012;122:2444-2453. [PMID: 22653059 DOI: 10.1172/jci61953] [Cited by in Crossref: 43] [Cited by in F6Publishing: 44] [Article Influence: 4.3] [Reference Citation Analysis]
Number Citing Articles
1 Oishi A, Jockers R. Recent Advances in Orphan GPCRs Research and Therapeutic Potential. GPCRs as Therapeutic Targets 2022. [DOI: 10.1002/9781119564782.ch2] [Reference Citation Analysis]
2 Gutiérrez-rojas RA, Aguayo-cerón KA, Vargas-de-león C, Cabrera-becerra SE, Almanza-pérez JC, Huang F, Villafaña S, Romero-nava R. Glycine Effect on the Expression Profile of Orphan Receptors GPR21, GPR26, GPR39, GPR82 and GPR6 in a Model of Inflammation in 3T3-L1 Cells. Life 2022;12:1687. [DOI: 10.3390/life12111687] [Reference Citation Analysis]
3 Mouat MA, Wilkins BP, Ding E, Govindaraju H, Coleman JLJ, Graham RM, Turner N, Smith NJ. Metabolic Profiling of Mice with Deletion of the Orphan G Protein-Coupled Receptor, GPR37L1. Cells 2022;11:1814. [DOI: 10.3390/cells11111814] [Reference Citation Analysis]
4 Bordano V, Kinsella GK, Cannito S, Dianzani C, Gigliotti CL, Stephens JC, Monge C, Bocca C, Rosa AC, Miglio G, Dianzani U, Findlay JB, Benetti E. G protein–coupled receptor 21 in macrophages: An in vitro study. European Journal of Pharmacology 2022. [DOI: 10.1016/j.ejphar.2022.175018] [Reference Citation Analysis]
5 Fahed G, Aoun L, Bou Zerdan M, Allam S, Bou Zerdan M, Bouferraa Y, Assi HI. Metabolic Syndrome: Updates on Pathophysiology and Management in 2021. Int J Mol Sci 2022;23:786. [PMID: 35054972 DOI: 10.3390/ijms23020786] [Cited by in Crossref: 61] [Cited by in F6Publishing: 56] [Article Influence: 61.0] [Reference Citation Analysis]
6 Riddy DM, Kammoun HL, Murphy AJ, Bosnyak-Gladovic S, De la Fuente Gonzalez R, Merlin J, Ziemann M, Fabb S, Pierce TL, Diepenhorst N, Rueda P, El-Osta A, Gautier JF, Venteclef N, Charman WN, Christopoulos A, Sexton PM, Summers RJ, Febbraio MA, Delerive P, Langmead CJ. Deletion of GPR21 improves glucose homeostasis and inhibits the CCL2-CCR2 axis by divergent mechanisms. BMJ Open Diabetes Res Care 2021;9:e002285. [PMID: 34782333 DOI: 10.1136/bmjdrc-2021-002285] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
7 Teng F, Tang W, Wuniqiemu T, Qin J, Zhou Y, Huang X, Wang S, Zhu X, Tang Z, Yi, Wei Y, Dong J. N 6-Methyladenosine Methylomic Landscape of Lung Tissues in Murine Acute Allergic Asthma. Front Immunol 2021;12:740571. [PMID: 34737744 DOI: 10.3389/fimmu.2021.740571] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 4.0] [Reference Citation Analysis]
8 Kinsella GK, Cannito S, Bordano V, Stephens JC, Rosa AC, Miglio G, Guaschino V, Iannaccone V, Findlay JBC, Benetti E. GPR21 Inhibition Increases Glucose-Uptake in HepG2 Cells. Int J Mol Sci 2021;22:10784. [PMID: 34639123 DOI: 10.3390/ijms221910784] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
9 Wada M, Yukawa K, Ogasawara H, Suzawa K, Maekawa T, Yamamoto Y, Ohta T, Lee E, Miki T. GPR52 accelerates fatty acid biosynthesis in a ligand-dependent manner in hepatocytes and in response to excessive fat intake in mice. iScience 2021;24:102260. [PMID: 33796846 DOI: 10.1016/j.isci.2021.102260] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
10 Shim K, Begum R, Yang C, Wang H. Complement activation in obesity, insulin resistance, and type 2 diabetes mellitus. World J Diabetes 2020;11:1-12. [PMID: 31938469 DOI: 10.4239/wjd.v11.i1.1] [Cited by in CrossRef: 41] [Cited by in F6Publishing: 38] [Article Influence: 20.5] [Reference Citation Analysis]
11 So SS, Ngo T, Keov P, Smith NJ, Kufareva I. Tackling the complexities of orphan GPCR ligand discovery with rationally assisted approaches. GPCRs 2020. [DOI: 10.1016/b978-0-12-816228-6.00016-7] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
12 Lackey DE, Reis FCG, Isaac R, Zapata RC, El Ouarrat D, Lee YS, Bandyopadhyay G, Ofrecio JM, Oh DY, Osborn O. Adipocyte PU.1 knockout promotes insulin sensitivity in HFD-fed obese mice. Sci Rep 2019;9:14779. [PMID: 31611602 DOI: 10.1038/s41598-019-51196-8] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 2.7] [Reference Citation Analysis]
13 Riddy DM, Kammoun H, Bosnyak-gladovic S, Ziemann M, Summers RJ, Sexton PM, Murphy AJ, Langmead CJ. Bone marrow transplantation and RNAseq analysis of Gpr21−/− monocytes reveals reduced migratory function and downregulation of inflammatory genes. Obesity Research & Clinical Practice 2019;13:291-292. [DOI: 10.1016/j.orcp.2018.11.162] [Reference Citation Analysis]
14 Morri M, Sanchez-Romero I, Tichy AM, Kainrath S, Gerrard EJ, Hirschfeld PP, Schwarz J, Janovjak H. Optical functionalization of human Class A orphan G-protein-coupled receptors. Nat Commun 2018;9:1950. [PMID: 29769519 DOI: 10.1038/s41467-018-04342-1] [Cited by in Crossref: 34] [Cited by in F6Publishing: 34] [Article Influence: 8.5] [Reference Citation Analysis]
15 Riddy DM, Goy E, Delerive P, Summers RJ, Sexton PM, Langmead CJ. Comparative genotypic and phenotypic analysis of human peripheral blood monocytes and surrogate monocyte-like cell lines commonly used in metabolic disease research. PLoS One 2018;13:e0197177. [PMID: 29746559 DOI: 10.1371/journal.pone.0197177] [Cited by in Crossref: 21] [Cited by in F6Publishing: 22] [Article Influence: 5.3] [Reference Citation Analysis]
16 Hernandez-Carretero A, Weber N, LaBarge SA, Peterka V, Doan NYT, Schenk S, Osborn O. Cysteine- and glycine-rich protein 3 regulates glucose homeostasis in skeletal muscle. Am J Physiol Endocrinol Metab 2018;315:E267-78. [PMID: 29634311 DOI: 10.1152/ajpendo.00435.2017] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 1.0] [Reference Citation Analysis]
17 Hinder LM, Murdock BJ, Park M, Bender DE, O'Brien PD, Rumora AE, Hur J, Feldman EL. Transcriptional networks of progressive diabetic peripheral neuropathy in the db/db mouse model of type 2 diabetes: An inflammatory story. Exp Neurol 2018;305:33-43. [PMID: 29550371 DOI: 10.1016/j.expneurol.2018.03.011] [Cited by in Crossref: 31] [Cited by in F6Publishing: 33] [Article Influence: 7.8] [Reference Citation Analysis]
18 Hernandez-Carretero A, Weber N, La Frano MR, Ying W, Lantero Rodriguez J, Sears DD, Wallenius V, Börgeson E, Newman JW, Osborn O. Obesity-induced changes in lipid mediators persist after weight loss. Int J Obes (Lond) 2018;42:728-36. [PMID: 29089614 DOI: 10.1038/ijo.2017.266] [Cited by in Crossref: 19] [Cited by in F6Publishing: 22] [Article Influence: 3.8] [Reference Citation Analysis]
19 Skarra DV, Hernández-Carretero A, Rivera AJ, Anvar AR, Thackray VG. Hyperandrogenemia Induced by Letrozole Treatment of Pubertal Female Mice Results in Hyperinsulinemia Prior to Weight Gain and Insulin Resistance. Endocrinology 2017;158:2988-3003. [PMID: 28911175 DOI: 10.1210/en.2016-1898] [Cited by in Crossref: 22] [Cited by in F6Publishing: 22] [Article Influence: 4.4] [Reference Citation Analysis]
20 Lackey DE, Lazaro RG, Li P, Johnson A, Hernandez-Carretero A, Weber N, Vorobyova I, Tsukomoto H, Osborn O. The role of dietary fat in obesity-induced insulin resistance. Am J Physiol Endocrinol Metab 2016;311:E989-97. [PMID: 27802965 DOI: 10.1152/ajpendo.00323.2016] [Cited by in Crossref: 17] [Cited by in F6Publishing: 18] [Article Influence: 2.8] [Reference Citation Analysis]
21 Leonard S, Kinsella GK, Benetti E, Findlay JBC. Regulating the effects of GPR21, a novel target for type 2 diabetes. Sci Rep 2016;6:27002. [PMID: 27243589 DOI: 10.1038/srep27002] [Cited by in Crossref: 15] [Cited by in F6Publishing: 16] [Article Influence: 2.5] [Reference Citation Analysis]
22 Baker M. Biotech giant publishes failures to confirm high-profile science. Nature 2016;530:141. [PMID: 26863961 DOI: 10.1038/nature.2016.19269] [Cited by in Crossref: 31] [Cited by in F6Publishing: 30] [Article Influence: 5.2] [Reference Citation Analysis]
23 Wang J, Pan Z, Baribault H, Chui D, Gundel C, Véniant M. GPR21 KO mice demonstrate no resistance to high fat diet induced obesity or improved glucose tolerance. F1000Res 2016;5:136. [PMID: 27081476 DOI: 10.12688/f1000research.7822.2] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 1.0] [Reference Citation Analysis]
24 Wang J, Pan Z, Baribault H, Chui D, Gundel C, Véniant M. GPR21 KO mice demonstrate no resistance to high fat diet induced obesity or improved glucose tolerance. F1000Res 2016;5:136. [PMID: 27081476 DOI: 10.12688/f1000research.7822.2] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 0.5] [Reference Citation Analysis]
25 Bernardo B, Lu M, Bandyopadhyay G, Li P, Zhou Y, Huang J, Levin N, Tomas EM, Calle RA, Erion DM, Rolph TP, Brenner M, Talukdar S. FGF21 does not require interscapular brown adipose tissue and improves liver metabolic profile in animal models of obesity and insulin-resistance. Sci Rep 2015;5:11382. [PMID: 26153793 DOI: 10.1038/srep11382] [Cited by in Crossref: 37] [Cited by in F6Publishing: 38] [Article Influence: 5.3] [Reference Citation Analysis]
26 Mayoral R, Osborn O, McNelis J, Johnson AM, Oh DY, Izquierdo CL, Chung H, Li P, Traves PG, Bandyopadhyay G, Pessentheiner AR, Ofrecio JM, Cook JR, Qiang L, Accili D, Olefsky JM. Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity. Mol Metab 2015;4:378-91. [PMID: 25973386 DOI: 10.1016/j.molmet.2015.02.007] [Cited by in Crossref: 104] [Cited by in F6Publishing: 95] [Article Influence: 14.9] [Reference Citation Analysis]
27 Fang S, Suh JM, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, Coulter S, Liddle C, Schoonjans K, Olefsky JM, Saltiel AR, Downes M, Evans RM. Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Nat Med. 2015;21:159-165. [PMID: 25559344 DOI: 10.1038/nm.3760] [Cited by in Crossref: 429] [Cited by in F6Publishing: 455] [Article Influence: 61.3] [Reference Citation Analysis]
28 Ahmad R, Wojciech S, Jockers R. Hunting for the function of orphan GPCRs - beyond the search for the endogenous ligand. Br J Pharmacol 2015;172:3212-28. [PMID: 25231237 DOI: 10.1111/bph.12942] [Cited by in Crossref: 30] [Cited by in F6Publishing: 31] [Article Influence: 3.8] [Reference Citation Analysis]
29 Perino A, Pols TW, Nomura M, Stein S, Pellicciari R, Schoonjans K. TGR5 reduces macrophage migration through mTOR-induced C/EBPβ differential translation. J Clin Invest 2014;124:5424-36. [PMID: 25365223 DOI: 10.1172/JCI76289] [Cited by in Crossref: 130] [Cited by in F6Publishing: 134] [Article Influence: 16.3] [Reference Citation Analysis]
30 Hodúlová M, Šedová L, Křenová D, Liška F, Krupková M, Kazdová L, Tremblay J, Hamet P, Křen V, Šeda O. Genomic determinants of triglyceride and cholesterol distribution into lipoprotein fractions in the rat. PLoS One 2014;9:e109983. [PMID: 25296178 DOI: 10.1371/journal.pone.0109983] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 0.8] [Reference Citation Analysis]
31 Saraswathi V, Ramnanan CJ, Wilks AW, Desouza CV, Eller AA, Murali G, Ramalingam R, Milne GL, Coate KC, Edgerton DS. Impact of hematopoietic cyclooxygenase-1 deficiency on obesity-linked adipose tissue inflammation and metabolic disorders in mice. Metabolism 2013;62:1673-85. [PMID: 23987235 DOI: 10.1016/j.metabol.2013.07.007] [Cited by in Crossref: 21] [Cited by in F6Publishing: 20] [Article Influence: 2.3] [Reference Citation Analysis]